56421-61-5 Usage
General Description
1-[4-Methyl-2-(2-thienyl)-1,3-thiazol-5-yl]-1-ethanone is a chemical compound with a thiazole ring attached to a thiophene ring and an ethanone group. It is a heterocyclic compound that is used in medicinal chemistry and organic synthesis. 1-[4-METHYL-2-(2-THIENYL)-1,3-THIAZOL-5-YL]-1-ETHANONE may have various applications, including as a building block for the synthesis of pharmaceuticals or other bioactive compounds. Its structure suggests that it may have potential biological activity, and further research and testing may be necessary to determine its exact properties and potential uses.
Check Digit Verification of cas no
The CAS Registry Mumber 56421-61-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,4,2 and 1 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 56421-61:
(7*5)+(6*6)+(5*4)+(4*2)+(3*1)+(2*6)+(1*1)=115
115 % 10 = 5
So 56421-61-5 is a valid CAS Registry Number.
InChI:InChI=1/C10H9NOS2/c1-6-9(7(2)12)14-10(11-6)8-4-3-5-13-8/h3-5H,1-2H3
56421-61-5Relevant articles and documents
Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyrase
Ronkin, Steven M.,Badia, Michael,Bellon, Steve,Grillot, Anne-Laure,Gross, Christian H.,Grossman, Trudy H.,Mani, Nagraj,Parsons, Jonathan D.,Stamos, Dean,Trudeau, Martin,Wei, Yunyi,Charifson, Paul S.
scheme or table, p. 2828 - 2831 (2010/08/19)
Bacterial DNA gyrase is an attractive target for the investigation of new antibacterial agents. Inhibitors of the GyrB subunit, which contains the ATP-binding site, are described in this communication. Novel, substituted 5-(1H-pyrazol-3-yl)thiazole compounds were identified as inhibitors of bacterial gyrase. Structure-guided optimization led to greater enzymatic potency and moderate antibacterial potency. Data are presented for the demonstration of selective enzyme inhibition of Escherichia coli GyrB over Staphlococcus aureus GyrB.
