56433-00-2

Usage

Uses

Used in Pharmaceutical Synthesis:
Benzene, 1-(bromomethyl)-3-chloro-2-nitrois utilized as an intermediate in the synthesis of pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Production:
Benzene, 1-(bromomethyl)-3-chloro-2-nitroalso finds use in the production of agrochemicals. Its properties make it suitable for the creation of pesticides and other agricultural chemicals that are designed to protect crops and enhance agricultural productivity.
Used in Dye Manufacturing:
Furthermore, Benzene, 1-(bromomethyl)-3-chloro-2-nitrois employed in the manufacturing of dyes. Its chemical structure plays a role in the color-producing capabilities of various dyes, which are used in a wide range of applications, from textiles to printing inks.
Environmental and Safety Considerations:

Upstream product

• 160088-65-3 4'-methyl-2',3'-dinitroacetanilide 
• 70343-09-8 2,3-dinitro-4-methylaniline 
• 2719-14-4 4-acetylamino-2-nitrotoluene 
• 5367-26-0 3-chloro-2-nitrotoluene 

Downstream Products

• 56433-02-4 2-(3-Chlor-2-nitro-benzyl)-2-acetamino-malonsaeure-diethylester 
• 887003-91-0 4-bromo-3-(3-chloro-2-nitro-benzylsulfanyl)-5-methyl-benzoic acid methyl ester 
• 56433-04-6 3-Chlor-2-nitro-phenylalanin 
• 56433-09-1 3-Chlor-2-amino-phenylalanin 

Relevant academic research and scientific papers

FUSED TRICYCLIC COMPOUNDS AS INHIBITORS OF TUMOR NECROSIS FACTOR-ALPHA

Compounds of formula (1): are disclosed, wherein V is CH2; W is S(O)m; m is the integer 0, 1 or 2; U is O, C(O), CR13R14 or NR15; where R13 is H, alkyl; R14 is H, OH, OR13 or OCOR13; R15 is H, alkyl, cycloalkyl, alkenyl, C(O)R13, C(O)OR13 or alkylaminocarbonyl; R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein. These compounds are inhibitor of tumor necrosis factor-alpha (TNF- ) and are useful as medicaments for the treatment and prevention of disorders caused by increased TNF- activity, in particular inflammations.

Polyaza Heterocycles. Part 2. Nucleophilic Substitution of Halogens in Halogenoquinoxalinocinnolines

10-Chloroquinoxalinocinnoline readily undergoes methoxydechlorination when treated with sodium methoxide.The 1-, 2-, 3-, 4- and 9-chloro isomers are unreactive towards this reagent, but the 9,10-dichloro derivative undergoes substitution of both chlorines (the 10-position being much the more reactive).The 9- and 10-bromo analogues are both unreactive towards sodium methoxide, but the 9- and 10-fluoro analogues are both highly reactive, to the extent that it has not been possible even to isolate the 10-fluoro compound.Routes to 9- and 10-piperidinoquinoxalinocinnolines are described.