56463-76-4

Usage

Chemical class

Pyrrole derivative

Functional groups

Amino group, Ketone functional group

Physical state

Yellow to orange crystalline solid

Usage

Organic intermediate in the synthesis of pharmaceuticals and agrochemicals

Biological activity

Potential biological activity, may have applications in research and development of new medications

Structure

Valuable building block in organic chemistry for the creation of more complex molecules

Research interest

Continued interest to scientists and pharmaceutical companies due to its versatile nature and potential therapeutic uses

InChI:InChI=1/C14H16N2O/c1-8-6-4-5-7-11(8)14-13(15)12(10(3)17)9(2)16-14/h4-7,16H,15H2,1-3H3

Upstream product

• 123-54-6 acetylacetone 
• 56464-73-4 DL-2-methylphenylglycine nitrile 

Downstream Products

• 57436-20-1 1-[4-(4-chloro-benzylamino)-2-methyl-5-o-tolyl-pyrrol-3-yl]-ethanone 

Relevant academic research and scientific papers

Aminopyrrole derivatives

Pharmacologically-active aminopyrrole derivatives of the formula STR1 wherein: R is selected from hydrogen, (C1-4)alkyl, benzyl and chlorobenzyl; R1 is selected from hydrogen, (C1-4)alkyl, phenyl and phenyl substituted by a radical selected from methyl, ethyl, methoxy, ethoxy, benzyloxy, fluoro, chloro and bromo; R2 and R3 individually represent hydrogen or (C1-4)alkyl or, taken together, represent an isopropylidene, a benzylidene or a chlorobenzylidene radical; R4 is selected from (C2-4)alkanoyl; carbo(C1-3)alkoxy; benzoyl, benzoyl substituted by a radical selected from chloro, methoxy or ethoxy; carbamoyl, methylcarbamoyl and phenyl carbamoyl; R5 is selected from hydrogen, (C1-4)alkyl, carbo(C1-3)alkoxy, carbomethoxymethyl, carbethoxymethyl, trifluoromethyl and carbamoyl, with the proviso that when R is hydrogen, R1 and R5 are methyl and R4 is carbethoxy, R2 and R3 cannot simultaneously represent hydrogen; And a salt thereof with a pharmaceutically acceptable acid. The compounds have anti-inflammatory and CNS-depressant utility. They are also useful as analgesics and antipyretics and display a very low degree of anti-ulcerogenic activity.