56471-69-3

Usage

Chemical structure

A complex structure consisting of a cycloheptane ring with an isopropyl group at one end and a 4-methoxy-2-methylphenyl group attached to the carboxamide functional group at the other end.

Functional group

Carboxamide, which means it contains an amide functional group.

Solubility

Likely to have some degree of solubility in organic solvents due to the presence of the isopropyl and methoxy groups.

Potential applications

May have potential applications in the pharmaceutical or agrochemical industries.

Research status

Further research is needed to fully understand its properties and potential uses.

InChI:InChI=1/C19H29NO2/c1-14(2)19(11-7-5-6-8-12-19)18(21)20-17-10-9-16(22-4)13-15(17)3/h9-10,13-14H,5-8,11-12H2,1-4H3,(H,20,21)

Relevant academic research and scientific papers

Aryl-substituted derivatives of cycloalkyl and branched chain alkyl carboxylic acids useful as antinociceptive drugs for peripheral targets

Novel peripheral antinociceptive compounds are disclosed having a pharmacophore unit that target small-diameter nerve fibers that transmit signals of pain and discomfort from the soma and viscera. By acting on this target, the pharmacophore unit obtunds pain and diminishes hyper-reflexia from organs such as the skin, the respiratory tract, the corpus, the lower urinary tract, and the bowel. The pharmacophore unit is coupled to substituents that facilitate delivery of the pharmacophore to its target.

Radioligands for the TRP-M8 receptor and methods therewith

One embodiment of the invention is a composition that comprises a radioactive [18F], [123I], [125I], or [131I]—N-radiohaloaryl-alkylcarboxamide molecule. The composition binds to the transient receptor potential-M8 (TRP-M8) receptor of cells. The TRP-M8 receptor is selectively expressed in sensory neurons and in malignant tissues such as prostate cancer cells. The [18F], [123I], [125I], or [131I]—N-radiohaloaryl-alkylcarboxamide ligand may be used for radioreceptor binding studies, for diagnostic studies, and for radiotherapy of cancerous tissues. Affinity of the [125I] or [131I]—N-radiohaloaryl-alkylcarboxamide ligand for the TRP-M8 receptor confers selectivity and specificity in delivering lethal radiation to the diseased cells.