56471-90-0

Usage

General Description

1,2-BENZENEDIAMINE, 4-(1-METHYLETHYL)-, also known as 4-methyl-1,2-phenylenediamine, is an organic compound that belongs to the family of aromatic amines. It is commonly used in the manufacturing of hair dyes and hair coloring products. This chemical functions as a dye intermediate, which means it is involved in the synthesis of hair colorants. It has a molecular formula of C8H12N2 and a molecular weight of 136.195 g/mol. 1,2-BENZENEDIAMINE, 4-(1-METHYLETHYL)- is classified as an irritant and can cause skin and eye irritation upon contact. It is important for individuals working with this chemical to use appropriate personal protective equipment and handle it with care to prevent adverse effects.

Upstream product

• 63649-64-9 4-isopropyl-2-nitrobenzenamine 

Downstream Products

• 103151-03-7 5-isopropyl-1,3-dihydro-benzimidazol-2-one 
• 1374771-55-7 2-chloro-6-isopropyl-1H-benzo[d]imidazole 

Relevant academic research and scientific papers

FGFR2 MODULATORS

A compound of Formula (I), or a pharmaceutically acceptable salt thereof, wherein:R3a, R2, R3b, R4b, L1, G and J are as defined in the specification, pharmaceutical compositionsthereof, and methods of use thereof.

SUBSTITUTED PIPERIDINES HAVING PROTEIN KINASE INHIBITING ACTIVITY

The invention provides PKA and PKB kinase-inhibiting compounds of the formula (I); or salts, solvates, tautomers or N-oxides thereof, wherein E is a five membered heteroaryl ring containing 1, 2, 3 or 4 heteroatoms selected from O, N and S provided that no more than 1 heteroatom may be other than N; q and r are each is 0 or 1; provided that q+r is 1 or 2; T is N or a group CR5; J1-J2 is N=C(R6), (R7)C=N, (R8)N- C(O), (R8)2C-C(O), N=N or (R7)C=C(R6); Q3 is a bond or a saturated C1-3 hydrocarbon linker group optionally substituted by fluorine and hydroxy; G is NR2R3, CN or OH; m and n are each 0 or 1, provided that m+n is 1 or 2, and provided also that m or n are each 0 when the adjacent ring member of ring E is S or O; R1a and R1b are the same or different and each is hydrogen or a substituent R10; or R1a and R1b together with the carbon atoms or heteroatoms to which they are attached form a 5 or 6-membered aryl or heteroaryl ring, wherein the aryl or heteroaryl rings are optionally substituted by one or more substituents R10; and R2, R3, R4, R5, R7, R6, R8, and R10 are as defined in the claims.

Perfluoroalkyl benzodiazepines

New perfluoroalkyl derivatives of benzodiazepine are prepared by reacting an orthophenylenediamine with a beta-diketone at least one of whose alkyls is a C1 - C15 perfluoroalkyl. The stable products are useful as heat-exchange substances and as surfactants in organic solution.