56479-75-5Relevant articles and documents
16-Member ring metal chelate
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Page/Page column 4, (2008/06/13)
Metal chelates are useful for improving the contrast of X-ray, ultrasound, radionuclide and magnetic resonance (MR) images. However, the metal complexes must be stable and inert so that toxicity resulting from dissociation in the body can be minimized. This invention provides 16-member ring metal chelates that can provide a charge balanced metal complex having improved stability, especially for gadolinium(III) and samarium (III).
Synthesis of Polyaza Macrocyclic Ligands Incorporating Pyridine Units
Hosseini, Mir Wais,Comarmond, Jacques,Lehn, Jean-Marie
, p. 1066 - 1077 (2007/10/02)
The synthesis of nine macrocyclic polyamines 2-10 containing pyridine units is described.These compounds are 22-(9), 24-(2-4,6,8,10), or 26-(5,7) membered hexaaza (2,3,9,10) or octaaza (4-7) macrocycles in which one to four pyridine units are incorporated