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1,4,7-triazacyclononane-N,N',N''-triacetic acid (NOTA) is a bifunctional chelating agent that exhibits a high complexation constant with metals, such as gallium. It is widely used in various applications due to its ability to form stable complexes with metal ions.

56491-86-2

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56491-86-2 Usage

Uses

Used in Medical Imaging:
1,4,7-triazacyclononane-N,N',N''-triacetic acid is used as a chelating agent for [enhancing the stability and solubility of metal-based imaging agents] in the medical imaging industry. NOTA forms stable complexes with metal ions, such as gallium, which can be used in diagnostic imaging techniques like positron emission tomography (PET) to improve the visualization of tumors and other abnormalities.
Used in Radiopharmaceuticals:
In the radiopharmaceutical industry, 1,4,7-triazacyclononane-N,N',N''-triacetic acid is used as a chelating agent for [improving the stability and biodistribution of radiolabeled compounds]. NOTA can be used to attach radioactive isotopes to targeting molecules, such as peptides or antibodies, to create radiopharmaceuticals that can be used for both diagnostic and therapeutic purposes in nuclear medicine.
Used in Drug Delivery Systems:
1,4,7-triazacyclononane-N,N',N''-triacetic acid is used as a chelating agent for [enhancing the targeting and delivery of therapeutic agents] in drug delivery systems. NOTA can be used to attach metal-based drugs or imaging agents to targeting molecules, improving their specificity and reducing off-target effects.
Used in Chemical Synthesis:
In the chemical synthesis industry, 1,4,7-triazacyclononane-N,N',N''-triacetic acid is used as a chelating agent for [facilitating the synthesis of metal complexes and coordination compounds]. NOTA can be used to stabilize metal ions during chemical reactions, making it easier to synthesize complex metal-containing compounds with specific properties and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 56491-86-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,4,9 and 1 respectively; the second part has 2 digits, 8 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 56491-86:
(7*5)+(6*6)+(5*4)+(4*9)+(3*1)+(2*8)+(1*6)=152
152 % 10 = 2
So 56491-86-2 is a valid CAS Registry Number.

56491-86-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[4,7-bis(carboxymethyl)-1,4,7-triazonan-1-yl]acetic acid

1.2 Other means of identification

Product number -
Other names 1H-1,4,7-Triazonine-1,4,7-triacetic acid,hexahydro

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:56491-86-2 SDS

56491-86-2Upstream product

56491-86-2Downstream Products

56491-86-2Relevant academic research and scientific papers

Lead(II) and Bismuth(III) Complexes of the Polyazacycloalkane-N-acetic Acids nota, dota, and teta

Kumar, Krishan,Magerstaedt, Michael,Gansow, Otto A.

, p. 145 - 146 (2007/10/02)

Lead(II) and bismuth(III) complexes of nota, dota, and teta were synthesized and their kinetic properties were investigated to show that the dota conplexes are the most inert over the pH range 4-12 and 1-10 for lead and bismuth, respectively.

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