56515-63-0 Usage
Uses
Used in Pharmaceutical Synthesis:
1-(2-Amino-6-nitrophenyl)ethanone is used as a versatile intermediate for the synthesis of various pharmaceuticals and organic compounds. Its unique structure with an amino group, nitro group, and ketone functional group allows for the development of a wide range of molecules with potential therapeutic applications.
Used in Chemical Research:
1-(2-Amino-6-nitrophenyl)ethanone is used as a research compound in the field of organic chemistry. Its properties and reactivity make it a valuable tool for studying various chemical reactions and mechanisms, contributing to the advancement of scientific knowledge.
Used in Drug Discovery and Development:
Due to its potential biological activities, 1-(2-Amino-6-nitrophenyl)ethanone may have applications in drug discovery and development. Its unique structure and functional groups can be utilized to design and synthesize new drug candidates with potential therapeutic benefits.
Check Digit Verification of cas no
The CAS Registry Mumber 56515-63-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,5,1 and 5 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 56515-63:
(7*5)+(6*6)+(5*5)+(4*1)+(3*5)+(2*6)+(1*3)=130
130 % 10 = 0
So 56515-63-0 is a valid CAS Registry Number.
56515-63-0Relevant academic research and scientific papers
Synthesis and biological assays of 9-(acylamino)homocamptothecins as DNA topoisomerase I inhibitors
Guo, Wei,Dong, Guoqiang,Zhu, Lingjian,Liu, Wenfeng,Zhuang, Chunlin,Guo, Zizhao,Yao, Jianzhong,Sheng, Chunquan,Zhang, Huojun,Miao, Zhenyuan,Zhang, Wannian
, p. 1804 - 1815 (2013/11/06)
In an effort to improve the stability of homocamptothecin and reduce the toxicity, novel homocamptothecin analogs with acylamino groups at C(9) were designed and synthesized. The cytotoxic activities of all the synthetic compounds against three cancer cell lines were evaluated by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay, and irinotecan was used as reference compound. Compound 7c with a piperidinylacetamido group and 10a with phenylacetamido group at C(9) showed potent activities both in vitro and in vivo. In addition, they also revealed remarkable topoisomerase I inhibitions which were exhibited with well-established bonds with amino acid residues Arg364 and Asp533 in the active pocket. On the basis of the biological activities, 7c and 10a would be potential candidates for further studies. Copyright
