565156-80-1Relevant articles and documents
Discovery of 5-substituted-N-arylpyridazinones as inhibitors of p38 MAP kinase
Jerome, Kevin D.,Hepperle, Michael E.,Walker, John K.,Xing, Li,Devraj, Rajesh V.,Benson, Alan G.,Baldus, John E.,Selness, Shaun R.
, p. 3146 - 3149 (2010)
The synthesis, structure-activity relationship and modeling of a series of 5-substituted-N-aryl pyridazinone based p38α inhibitors are described. In comparing the series to the similar N-aryl pyridinone series, it was found that the pyridazinones maintain