565176-62-7Relevant academic research and scientific papers
Giving a Second Chance to Ir/Sulfoximine-Based Catalysts for the Asymmetric Hydrogenation of Olefins Containing Poorly Coordinative Groups
Biosca, Maria,Pàmies, Oscar,Diéguez, Montserrat
, p. 8259 - 8266 (2019/06/17)
This work identifies a family of Ir/phosphite-sulfoximine catalysts that has been successfully used in the asymmetric hydrogenation of olefins with poorly coordinative or noncoordinative groups. In comparison with analogue Ir/phosphine-sulfoximine catalysts previously reported, the presence of a phosphite group extended the range of olefins than can be efficiently hydrogenated. High enantioselectivities, comparable to the best ones reported, have been achieved for a wide range of olefins containing relevant poorly coordinative groups such as α,β-unsaturated enones, esters, lactones, and lactams as well as alkenylboronic esters.
New chiral benzothiazine ligand and its use in the synthesis of a chiral receptor
Harmata, Michael,Calkins, Nathan L.,Baughman, Russell G.,Barnes, Charles L.
, p. 3650 - 3652 (2007/10/03)
The development of chiral ligands to direct the course and stereoselectivity of many catalytic asymmetric reactions is an important area of interest for many research groups. As part of a program examining the chemistry of 2,1-benzothiazines, we have prep
Studies towards the total synthesis of mumbaistatin: Synthesis of highly substituted benzophenone and anthraquinone building blocks
Kaiser, Florian,Schwink, Lothar,Velder, Janna,Schmalz, Hans-Günther
, p. 3201 - 3217 (2007/10/03)
Model compounds and building blocks for a planned total synthesis of the highly potent glucose-6-phosphate (G6P) translocase inhibitor mumbaistatin (1) and structural analogs were elaborated: compound 1 represents a lead structure in the development of po
