56526-46-6

Upstream product

• 56553-17-4 (S)-2-((1S)-3-benzyl-7-oxo-(1rH,5cH)-4-oxa-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-mercapto-3-methyl-butyric acid methyl ester; mercury(II) salt (2:1) 
• 113-98-4 Penicillin G potassium 
• 74-88-4 methyl iodide 
• 186581-53-3 diazomethane 
• 49841-84-1 (S)-2-((1S)-3-benzyl-7-oxo-4-oxa-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-mercapto-3-methyl-butyric acid methyl ester 

Downstream Products

• 71840-43-2 methyl 2-(2,4-dioxo-3-phenylacatamidoazetidin-1-yl)-3-methylbut-2-enoate 
• 121003-04-1 methyl (2S)-3-methyl-3-methylthio-2-<(3S,4S)-2-oxo-3-phenylacetamido-4-pyruvoyloxyazetidin-1-yl>butanoate 
• 34104-19-3 methyl 2-<(1S,5R)-3-benzyl-7-oxo-4-oxa-2,6-diazabicyclo<3.2.0>hept-2-en-6-yl>-3-methylbut-2-enoate 
• 56526-47-7 (S)-2-((1S)-3-benzyl-7-oxo-(1rH,5cH)-4-oxa-2,6-diaza-bicyclo[3.2.0]hept-2-en-6-yl)-3-(Ξ)-methanesulfinyl-3-methyl-butyric acid methyl ester 

Relevant academic research and scientific papers

STUDIES RELATED TO PENICILLINS. PART 26. CONVERSION OF POTASSIUM BENZYLPENICLLINATE INTO 1-SUBSTITUTED DERIVATIVES OF 3-PHENYL-ACETAMIDOAZETIDINE-2,4-DIONE

A new method for the synthesis of azetidine-2,4-diones, involving a Norrish Type II photoreaction of 4-pyruvoylazetidin-2-ones, has been devised.The process features in strategies in which potassium benzylpenicillinate (17a) is converted into 1-substitute