565430-72-0

Upstream product

• 186581-53-3 diazomethane 
• 507276-74-6 Boc-D-Tyr(t-Bu)-OH 

Downstream Products

• 507276-94-0 [1-(4-tert-butoxy-benzyl)-3-hydroxy-pent-4-enyl]-carbamic acid tert-butyl ester 
• 507276-92-8 [1-(4-tert-butoxy-benzyl)-3-hydroxy-pent-4-enyl]-carbamic acid tert-butyl ester 
• 565430-83-3 [1-(4-tert-butoxy-benzyl)-3-oxo-propyl]-carbamic acid tert-butyl ester 

Relevant academic research and scientific papers

MU OPIOID RECEPTOR LIGANDS: METHODS OF USE AND SYNTHESIS

Peptidomimetic compounds derived from aralkyl substitued 8-amino-3,7- or 3,6-dihydroxy alkenoic or alkanoic acids and compositions including those compounds, as well as methods of using and making the compounds are herein described. The compounds are usef

Unpredictable stereochemical preferences for mu opioid receptor activity in an exhaustively stereodiversified library of 1,4-enediols.

Using olefin cross-metathesis, we synthesized a novel stereodiversified library of compounds 3 containing a trans-1,4-enediol. Screening this library for mu opioid receptor (MOR) affinity identified multiple high-affinity ligands and revealed that the ste