565430-82-2Relevant academic research and scientific papers
Unpredictable stereochemical preferences for mu opioid receptor activity in an exhaustively stereodiversified library of 1,4-enediols.
Shi, Zhangjie,Harrison, Bryce A,Verdine, Gregory L
, p. 633 - 636 (2003)
Using olefin cross-metathesis, we synthesized a novel stereodiversified library of compounds 3 containing a trans-1,4-enediol. Screening this library for mu opioid receptor (MOR) affinity identified multiple high-affinity ligands and revealed that the ste
