565442-00-4Relevant academic research and scientific papers
Cu-Catalyzed Regioselective C-H Alkylation of Benzimidazoles with Aromatic Alkenes
He, Yu-Ting,Mao, Yang-Jie,Hao, Hong-Yan,Xu, Zhen-Yuan,Lou, Shao-Jie,Xu, Dan-Qian
supporting information, p. 8250 - 8255 (2020/11/18)
Herein we report a novel Cu-catalyzed regioselective C2-H alkylation of benzimidazoles with aromatic alkenes. The reaction features exclusive regioselectivity and broad substrate scope in the intermolecular alkylation of benzimidazoles with terminal and i
Immobilized catalysts for iridium-catalyzed allylic amination: Rate enhancement by immobilization
Malakar, Chandi C.,Helmchen, Günter
supporting information, p. 7127 - 7134 (2015/05/05)
The first immobilized catalyst for Ir-catalyzed asymmetric allylic aminations is described. The catalyst is a cationic (π-allyl)Ir complex bound by cation exchange to an anionic silica gel support. Preparation of the catalyst is facile, and the supported
Synthesis, characterization and microwave-assisted catalytic activity of novel benzimidazole salts bearing piperidine and morpholine moieties in Heck cross-coupling reactions
Kuecuekbay, Hasan,Sireci, Nihat,Yilmaz, Uelkue,Akkurt, Mehmet,Yalcin, Serife Pinar,Nawaz Tahir,Ott, Holger
experimental part, p. 255 - 261 (2012/01/04)
A mixture of novel benzimidazole salts (2a-f), Pd(OAc)2 and K2CO3 in DMF-H2O catalyzes, in high yield, the Heck cross-coupling reaction assisted by microwave irradiation in a short time. All synthesized novel benzimidazole derivatives were characterized by elemental analysis and NMR spectroscopy. In addition, the molecular structure of 2a was determined by X-ray crystallography.
Regio- and enantioselective N-allylations of imidazole, benzimidazole, and purine heterocycles catalyzed by single-component metallacyclic iridium complexes
Stanley, Levi M.,Hartwig, John F.
supporting information; experimental part, p. 8971 - 8983 (2009/12/04)
Highly regio- and enantioselective iridium-catalyzed N-allylations of benzimidazoles, imidazoles, and purines have been developed. N-Allylated benzimidazoles and imidazoles were isolated in high yields (up to 97%) with high branched-to-linear selectivity
Microwave-assisted C-H bond activation: A rapid entry into functionalized heterocycles
Tan, Kian L.,Vasudevan, Anil,Bergman, Robert G.,Ellman, Jonathan A.,Souers, Andrew J.
, p. 2131 - 2134 (2007/10/03)
(Matrix presented) Microwave irradiation strongly accelerates the rhodium-catalyzed intramolecular coupling of a benzimidazole C-H bond to pendant alkenes. The cyclic products were formed in moderate to excellent yields with reaction times less than 20 min. Additionally, the use of microwave irradiation allowed the reactions to be performed without any solvent purification and with minimal precautions to exclude air.
