565448-79-5 Usage
General Description
1-isopentyl-1H-pyrido[2,3-d][1,3]oxazine-2,4-dione, also known as thalidomide, is a synthetic derivative of glutamic acid. It was originally developed as a sedative and hypnotic medication, but was later found to have teratogenic effects, leading to severe birth defects when taken during pregnancy. Thalidomide has found renewed interest in recent years for its immunomodulatory and anti-inflammatory properties, and is used in the treatment of conditions such as leprosy, multiple myeloma, and certain autoimmune diseases. It is also being investigated for its potential in treating various cancers, HIV/AIDS, and other inflammatory disorders. Thalidomide is classified as a teratogen, and strict measures are in place to prevent its use during pregnancy or in women of childbearing potential without adequate contraception.
Check Digit Verification of cas no
The CAS Registry Mumber 565448-79-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,6,5,4,4 and 8 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 565448-79:
(8*5)+(7*6)+(6*5)+(5*4)+(4*4)+(3*8)+(2*7)+(1*9)=195
195 % 10 = 5
So 565448-79-5 is a valid CAS Registry Number.
InChI:InChI=1/C12H14N2O3/c1-8(2)5-7-14-10-9(4-3-6-13-10)11(15)17-12(14)16/h3-4,6,8H,5,7H2,1-2H3
565448-79-5Relevant articles and documents
Anti-infective agents
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Page 40, (2010/02/06)
Compounds having the formula are hepatitis C (HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C (HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.
Anti-infective agents
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, (2008/06/13)
Compounds having the formula are hepatitis C(HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C(HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.
