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5655-00-5

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5655-00-5 Usage

General Description

1H-Pyrrolo[3,4-c]pyridin-1-one, 2,3-dihydro- is a heterocyclic compound with a molecular formula C7H7NO. It is a derivative of pyrrolopyridine and is also known as norharmane. This chemical is naturally occurring in foods such as coffee and tobacco smoke, and it is also found in various plants and animals. It has been studied for its potential biological activities, including its role as a neurotoxin and its potential as an anticancer agent. 1H-Pyrrolo[3,4-c]pyridin-1-one, 2,3-dihydro- is also used as a building block in organic synthesis, and its derivatives have been investigated for their potential pharmaceutical applications.

Check Digit Verification of cas no

The CAS Registry Mumber 5655-00-5 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,5 and 5 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 5655-00:
(6*5)+(5*6)+(4*5)+(3*5)+(2*0)+(1*0)=95
95 % 10 = 5
So 5655-00-5 is a valid CAS Registry Number.

5655-00-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 2,3-dihydropyrrolo[3,4-c]pyridin-1-one

1.2 Other means of identification

Product number -
Other names 1H,2H,3H-PYRROLO[3,4-C]PYRIDIN-1-ONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5655-00-5 SDS

5655-00-5Upstream product

5655-00-5Relevant articles and documents

Synthesis and biological activity of conformationally restricted indole-based inhibitors of neurotropic alphavirus replication: Generation of a three-dimensional pharmacophore

Barraza, Scott J.,Sindac, Janice A.,Dobry, Craig J.,Delekta, Philip C.,Lee, Pil H.,Miller, David J.,Larsen, Scott D.

supporting information, (2021/06/18)

We have previously reported the development of indole-based CNS-active antivirals for the treatment of neurotropic alphavirus infection, but further optimization is impeded by a lack of knowledge of the molecular target and binding site. Herein we describe the design, synthesis and evaluation of a series of conformationally restricted analogues with the dual objectives of improving potency/selectivity and identifying the most bioactive conformation. Although this campaign was only modestly successful at improving potency, the sharply defined SAR of the rigid analogs enabled the definition of a three-dimensional pharmacophore, which we believe will be of value in further analog design and virtual screening for alternative antiviral leads.

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