56563-86-1

Basic information

• Product Name: 1-Butanone, 3-methyl-1-phenyl-3-(phenylthio)-
• CAS NO: 56563-86-1
• Molecular Formula: C17H18OS
• Molecular Weight: 270.395
• Mol File: 56563-86-1.mol

Chemical Properties

• CAS DataBase Reference: 1-Butanone, 3-methyl-1-phenyl-3-(phenylthio)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Butanone, 3-methyl-1-phenyl-3-(phenylthio)-(56563-86-1)
• EPA Substance Registry System: 1-Butanone, 3-methyl-1-phenyl-3-(phenylthio)-(56563-86-1)

Safety Data

• Hazardous Substances Data: 56563-86-1(Hazardous Substances Data)

Upstream product

• 5650-07-7 3-methyl-1-phenyl-but-2-en-1-one 
• 108-98-5 thiophenol 

Relevant articles and documents

The iron(III) chloride-mediated 1,4-addition of mercaptans to α,β-unsaturated ketones and esters under solvent free conditions

The 1,4-addition of various thiols to α,β-unsaturated ketones was completed rapidly in the presence of a catalytic amount (2-3 mol %) of anhydrous iron(III) chloride under solvent free conditions and an air atmosphere. Anhydrous iron(III) chloride is more active than that of other ferric salts. With more reactive and/or less steric reagents (1a-c and/or 2a-2c), expeditious conditions (short reaction times at room temperature) could be employed. With less reactive and/or steric reagents (1d-g and/or 2d-e), a slight increase in reaction time was required, but high yields were obtained. The FeCl3 catalyst causes preferential interactions with α,β-unsaturated ketones present in the reaction.

Ceric ammonium nitrate (CAN) as a green and highly efficient promoter for the 1,4-addition of thiols and benzeneselenol to α,β-unsaturated ketones

A mild and efficient process for the 1,4-addition of thiols and benzeneselenols to various α,β-unsaturated ketones using a catalytic amount of CAN with excellent product yields is described. This inexpensive, nontoxic, and readily available catalytic ceric(IV) ammonium nitrate system efficiently catalyzes conjugate addition reactions between thiol derivatives and various α,β-unsaturated ketones under solvent-free conditions. A plausible mechanism for the role of CAN, both as a promoter in free radical chain addition reactions as well as a catalyst for the conjugate addition process is proposed.

Iodine-catalyzed Michael addition of mercaptans to α,β- unsaturated ketones under solvent-free conditions

A simple and efficient method for the Michael reaction between various mercaptans and α,β-unsaturated ketones using a catalytic amount of iodine (5 mol %) to generate the 1,4-adduct has been reported. The significant features of the iodine catalyzed Micha