56598-68-6Relevant academic research and scientific papers
Concerted Catalysis by Adjacent Palladium and Gold in Alloy Nanoparticles for the Versatile and Practical [2+2+2] Cycloaddition of Alkynes
Miura, Hiroki,Tanaka, Yumi,Nakahara, Karin,Hachiya, Yuka,Endo, Keisuke,Shishido, Tetsuya
supporting information, p. 6136 - 6140 (2018/05/03)
A Pd-Au alloy efficiently catalyzed the [2+2+2] cycloaddition of substituted alkynes. Whereas monometallic Pd and Au catalysts were totally ineffective, Pd-Au alloy nanoparticle catalysts with a low Pd/Au molar ratio showed high activity to give the corresponding polysubstituted arenes in high yields. A variety of substituted alkynes participated in various modes of cycloaddition under Pd-Au alloy catalysis. The Pd-Au alloy catalysts exhibited high air tolerance and reusability.
Chiral N-phosphino sulfinamide ligands in rhodium(I)-catalyzed [2+2+2] cycloaddition reactions
Brun, Sandra,Parera, Magda,Pla-Quintana, Anna,Roglans, Anna,León, Thierry,Achard, Thierry,Sol, Jordi,Verdaguer, Xavier,Riera, Antoni
experimental part, p. 9032 - 9040 (2011/01/04)
The combination of cationic rhodium(I) complexes with N-phosphino tert-butylsulfinamides (PNSO) ligands is efficient for catalytic intra- and intermolecular [2+2+2] cycloaddition reactions. PNSO ligands are a new class of chiral bidentate ligands, which h
Rhodium-catalyzed selective [2 + 2 + 2] cyclizations of 1,6-diynes with monoynes leading to isoindolines and isobenzofurans
Wu, Wei,Zhang, Xiao Yun,Kang, Shou Xing
experimental part, p. 18 - 22 (2010/11/16)
A highly efficient and selective [2 + 2 + 2] cyclization of diynes and monoalkynes was catalyzed by rhodium under room temperature in water/THF mixed solvent, affording isoindolines and isobenzofurans in good to excellent yields. The center atoms (N, O) i
Formal radical closure onto aromatic rings-a general route to carbocycles
Clive, Derrick L. J.,Sunasee, Rajesh,Chen, Zhenhua
experimental part, p. 2434 - 2441 (2009/02/02)
A general method is described for indirectly effecting radical carbocyclization of an alkyl chain onto an aromatic ring. Birch reductive-alkylation of aromatic tert-butyl esters with α,ω- dibromides, chromium(vi)-mediated oxidation of the resulting 1,4-dienes and Finkelstein displacement of Br- with NaI gives cross-conjugated ketones that undergo radical cyclization. The products are easily aromatized to phenols by silylation, Saegusa oxidation and treatment with BiCl 3.H2O. A special feature of the route is that it allows attachment of a substituent to the original aromatic ring in place of the phenolic oxygen of the normal product.
Rhodium-catalysed -Cycloadditions of Acteylenes
Grigg, Ronald,Scott, Ronald,Stevenson, Paul
, p. 1357 - 1364 (2007/10/02)
Wilkinson's catalyst (0.5-2 molpercent) catalyses the chemospecific -cycloaddition of hepta-1,6-diynes with monoynes to give polysubstituted benzene derivatives in moderate to good yield.The reaction is favoured by polar solvents such as ethanol and occurs at 0-78 deg C.Several examples of intramolecular -cycloadditions of triynes are described and a mechanism that accounts for the chemospecificty and observed variations in rates of reaction is discussed.
