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[2-(3-chloro-phenyl)-2-hydroxy-ethyl]-[2-(7-hydroxy-1H-indol-3-yl)-1-methyl-ethyl]-carbamic acid tert-butyl ester is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

566200-65-5

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566200-65-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 566200-65-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,6,6,2,0 and 0 respectively; the second part has 2 digits, 6 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 566200-65:
(8*5)+(7*6)+(6*6)+(5*2)+(4*0)+(3*0)+(2*6)+(1*5)=145
145 % 10 = 5
So 566200-65-5 is a valid CAS Registry Number.

566200-65-5Relevant academic research and scientific papers

Novel and potent human and rat β3-adrenergic receptor agonists containing substituted 3-indolylalkylamines

Harada, Hiroshi,Hirokawa, Yoshimi,Suzuki, Kenji,Hiyama, Yoichi,Oue, Mayumi,Kawashima, Hitoshi,Yoshida, Naoyuki,Furutani, Yasuji,Kato, Shiro

, p. 1301 - 1305 (2007/10/03)

A novel series of 2-(3-indolyl)alkylamino-1-(3-chlorophenyl)ethanols was prepared and evaluated for in vitro ability to stimulate cAMP production in Chinese hamster ovary cells expressing cloned human β3-AR. The optically active 30a was found to be the most potent and selective human β3-AR agonist in this series with an EC50 value of 0.062 nM. In addition, 30a selectivity for human β3-AR was 210-fold and 103-fold that for human β2-AR and β1-AR, respectively. Furthermore, 30a showed potent agonistic activity at rat β3-AR.

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