566202-58-2Relevant academic research and scientific papers
A new method of N-benzhydryl deprotection in 2-azetidinone series
Laurent, Mathieu,Belmans, Marc,Kemps, Luc,Ce?re?siat, Marcel,Marchand-Brynaert, Jacqueline
, p. 570 - 576 (2007/10/03)
A mild and efficient procedure for the selective cleavage of N-benzhydryl protecting group of β-lactams is described. The protected 2-azetidinones 4, precursors of carbapenems, were treated with a stoichiometric amount of N-bromosuccinimide and a catalyti
