566204-86-2

Upstream product

• 566203-62-1 2,3-dichloro-N-(5-chloro-3-methoxy-2-pyrazinyl)benzenesulphonamide 
• 76513-69-4 (2-trimethylethylsilylethoxy)methyl chloride 
• 82417-45-6 dichlorobenzenesulfonyl chloride 
• 566203-96-1 2,3-dichloro-N-(3,5-dichloro-2-pyrazinyl)benzenesulphonamide 

Downstream Products

• 808139-25-5 N-[5-[[(2R)-2-amino-2-phenylethyl]oxy]-3-methoxypyrazin-2-yl]-2,3-dichloro-N-[[2-(trimethylsilyl)ethoxy]methyl]-benzenesulfonamide 
• 808139-27-7 2-[[5-[[(2,3-dichlorophenyl)sulfonyl][[2-(trimethylsilyl)ethoxy]methyl]amino]-6-methoxypyrazin-2-yl]thio]-N-methoxy-N-methyl-acetamide 
• 808139-43-7 3-[[5-[[(2,3-dichlorophenyl)sulfonyl][[2-(trimethylsilyl)ethoxy]methyl]amino]-6-methoxypyrazin-2-yl]thio]-(2R)-2-hydroxypropanoic acid methyl ester 
• 808139-30-2 2,3-dichloro-N-[5-[[2-hydroxy-2-(1-methyl-1H-imidazol-2-yl)ethyl]thio]-3-methoxypyrazin-2-yl]-N-[[2-(trimethylsilyl)ethoxy]methyl]-benzenesulfonamide 
• 808139-35-7 2,3-dichloro-N-[3-methoxy-5-[(2-oxo-2-phenylethyl)thio]pyrazin-2-yl]-N-[[2-(trimethylsilyl)ethoxy]methyl]benzenesulfonamide 
• 808139-36-8 2,3-dichloro-N-[5-[(2-hydroxy-2-phenylethyl)thio]-3-methoxypyrazin-2-yl]-N-[[2-(trimethylsilyl)ethoxy]methyl]benzenesulfonamide 
• 808139-28-8 2,3-dichloro-N-[3-methoxy-5-[[2-oxo-2-(2-thiazolyl)ethyl]thio]pyrazin-2-yl]-N-[[2-(trimethylsilyl)ethoxy]methyl]-benzenesulfonamide 
• 808139-18-6 [(1R)-2-[[5-[[(2,3-dichlorophenyl)sulfonyl][[2-(trimethylsilyl)ethoxy]methyl]amino]-6-methoxypyrazin-2-yl]thio]-1-(hydroxymethyl)ethyl]carbamic acid 1,1-dimethylethyl ester 
• 808139-15-3 [(1R)-2-amino-1-[[[5-[[(2,3-dichlorophenyl)sulfonyl][[2-(trimethylsilyl)ethoxy]methyl]amino]-6-methoxypyrazin-2-yl]thio]methyl]-2-oxoethyl]carbamic acid 1,1-dimethylethyl ester 
• 808139-14-2 S-[5-[[(2,3-dichlorophenyl)sulfonyl][[2-(trimeihylsilyl)ethoxy]methyl]amino]-6-methoxypyrazin-2-yl]-N-[(1,1-dimethylethoxy)carbonyl]-L-cysteine 
• 808139-29-9 2,3-dichloro-N-[3-methoxy-5-[[(trimethylsilyl)methyl]thio]pyrazin-2-yl]-N-[[2-(trimethylsilyl)ethoxy]methyl]-benzenesulfonamide 
• 808139-12-0 S-[5-[[(2,3-dichlorophenyl)sulfonyl][[2-(trimeihylsilyl)ethoxy]methyl]amino]-6-methoxypyrazin-2-yl]-D-cysteine methyl ester 
• 808139-26-6 2,3-dichloro-N-[3-methoxy-5-[[2-(4-pyridinyl)ethyl]thio]pyrazin-2-yl]-N-[[2-(trimethylsilyl)ethoxy]methyl]-benzenesulfonamide 
• 808139-58-4 C₂₈H₄₂Cl₂N₄O₈SSi 

Relevant academic research and scientific papers

SULPHONAMIDE COMPOUNDS THAT MODULATE CHEMOKINE RECEPTOR ACTIVITY (CCR4)

The invention relates to sulphonamide compounds, processes and intermediates used in their preparation, pharmaceutical compositions containing them and their use in therapy.