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2-Bromopyrimidin-5-amine is an organic compound with the molecular formula C4H4BrN3. It is a heterocyclic compound featuring a pyrimidine ring with a bromine atom at the 2nd position and an amino group at the 5th position. This chemical structure endows it with specific reactivity and properties that make it useful in various applications, particularly in the pharmaceutical and chemical industries.

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  • 56621-91-1 Structure
  • Basic information

    1. Product Name: 2-BROMOPYRIMIDIN-5-AMINE
    2. Synonyms: 2-BROMOPYRIMIDIN-5-AMINE;5-AMINO-2-BROMOPYRIMIDINE;5-PYRIMIDINAMINE, 2-BROMO-;2-Bromo-5- aminepyrimidine;2-BroMopyriMidine-5-aMine;2-bromo-5-Pyrimidinamine
    3. CAS NO:56621-91-1
    4. Molecular Formula: C4H4BrN3
    5. Molecular Weight: 174
    6. EINECS: N/A
    7. Product Categories: Heterocycle-Pyrimidine series
    8. Mol File: 56621-91-1.mol
  • Chemical Properties

    1. Melting Point: 182-183 °C(Solv: benzene (71-43-2))
    2. Boiling Point: 364.137 °C at 760 mmHg
    3. Flash Point: 174.024 °C
    4. Appearance: /
    5. Density: 1.844 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. PKA: -0.15±0.10(Predicted)
    10. CAS DataBase Reference: 2-BROMOPYRIMIDIN-5-AMINE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-BROMOPYRIMIDIN-5-AMINE(56621-91-1)
    12. EPA Substance Registry System: 2-BROMOPYRIMIDIN-5-AMINE(56621-91-1)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 56621-91-1(Hazardous Substances Data)

56621-91-1 Usage

Uses

Used in Pharmaceutical Industry:
2-Bromopyrimidin-5-amine is used as a reagent for the synthesis of a bioavailable PPARα antagonist. This application is significant in the treatment of metabolic syndrome, a cluster of conditions that increase the risk of heart disease, stroke, and type 2 diabetes. 2-Bromopyrimidin-5-amine's unique structure allows it to be a key component in the development of drugs targeting metabolic disorders.

Check Digit Verification of cas no

The CAS Registry Mumber 56621-91-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,6,2 and 1 respectively; the second part has 2 digits, 9 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 56621-91:
(7*5)+(6*6)+(5*6)+(4*2)+(3*1)+(2*9)+(1*1)=131
131 % 10 = 1
So 56621-91-1 is a valid CAS Registry Number.

56621-91-1Upstream product

56621-91-1Relevant articles and documents

N-heterocyclyl sulphonamide derivatives and their use as endothelin antagonists

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, (2008/06/13)

The invention concerns pharmaceutically useful N-heterocyclyl sulphonamide derivatives, their pharmaceutically acceptable salts, processes for their manufacture, their use for antagonising one or more actions of endothelin in a human or other warm-blooded animal, their use in methods of treatment of diseases or medical conditions in which elevated or abnormal levels of endothelin play a significant causative role.

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