56642-91-2Relevant academic research and scientific papers
SYNTHESIS OF 4-ARYL BENZIMIDAZOLO-s-TRIAZIN-2-ONES AND 2-AROYLAMINOBENZIMIDAZOLO-1,2,4-THIADIAZOLINES
Sridevi, G.,Rao, P. Jayaprasad,Reddy, K. Kondal
, p. 965 - 972 (2007/10/02)
Reaction of 2-aminobenzimidazole with aroylisothiocyanates gave 2-aroylaminobenzimidazoles (3) and N-aroyl-N'-(benzimidazol-2-yl)-thioureas (4).The products obtained on reaction of 4 with PCl5 in POCl3 , and with oxidising agents have been identified as 4
2-PHENYL- AND 2-BENZAMIDO-BENZIMIDAZOLES
Sluka, Jaroslav,Danek, Jaroslav,Bedrnik, Petr,Budesinsky, Zdenek
, p. 2703 - 2708 (2007/10/02)
2-Phenylbenzimidazoles I-VI with chlorine atom or methoxy group on the benzene ring were prepared by a modified method.Acylation of 2-aminobenzimidazoles with substituted benzoyl chlorides afforded the 2-benzamidobenzimidazoles VII-XXXVI.All these compounds were tested for anthelmintic and coccidiostatic activity.
Reactions with N-Acylimino-dithiocarbonic-acid-diesters
Augustin, M.,Richter, M.,Salas, S.
, p. 55 - 68 (2007/10/02)
Reactions of N-acylimino-dithiocarbonic-acid-S,S-diesters 1 with nucleophilic compounds present new possibilities to synthesize heterocycles.With amines 1a reacts by mono- and disubstitution, respectively, of methylthio-groups to isothioureas 2 and guanidines 3, with 1,2-binucleophilic arenes to benzoheterocycles 4, with aliphatic diamines to imidazolines 5, pyrimidines 6, diazepines 7 and the hexamethylene-diamine-derivatives 8. 1a reacts also with hydrazines to 1,2,4-triazoles 9 and with hydrazides to the thiosemicarbazones 10 or 1,3,4-oxadiazoles 11.Heterocyclisations of 1 with guanidines, thiourea, salts of thiourea and amidines give the 1,3,5-triazines 12, 14, 15 and 16.N-benzoyl-dithiocarbonic-acid-methylester -amid reacts with CH-acidic compounds to thiazoles 17.The structures of the final products are determined by i.r.-, 1H-n.m.r.-, u.v.- and mass-spectras.
