56648-98-7Relevant articles and documents
2-Substituted phenyl-6-trifluoromethyl-4-pyridyl-carbinolamines
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, (2008/06/13)
A series of 2-aryl-6-trifluoromethyl-4-pyridylcarbinolamines is herein disclosed which has value in treatment of plasmodial infections. The compounds have substituted phenyl groups at position 2- on the pyridine moiety, with the electronegative substituents present on the phenyl nuclei. The syntheses of such series is described, together with a method for separation of racemates of a representative 4-pyridylcarbinolamine type.