56657-86-4

Upstream product

• 929097-02-9 C₁₆H₁₇F₂NO₃S 
• 475152-29-5 C₁₁H₁₂N₂O₂*ClH 
• 37663-42-6 1'-benzylspiro[isobenzofuran-1(3H),4'-piperidine]-3-one 

Relevant academic research and scientific papers

FUSED AND SPIROCYCLE COMPOUNDS AND THE USE THEREOF

The invention relates to fused and spirocycle compounds of Formula (I), or a pharmaceutically acceptable salt, prodrug, or solvate thereof, wherein R1, R2, Q1-Q3, and Z are defined as set forth in the specification. The invention is also directed to the use of compounds of Formula (I) to treat, prevent or ameliorate a disorder responsive to the blockade of calcium channels, and particularly N-type calcium channels. Compounds of the present invention are especially useful for treating pain.

1,3-Dihydrospiro[isobenzofuran]s and derivatives thereof

Novel substituted 1,3-dihydrospiro[isobenzofuran]s and methods of preparing the same are described. These compounds are useful as tranquilizers, analgetic agents and intermediates therefor.