5666-77-3Relevant academic research and scientific papers
From diols to lactones under aerobic conditions using a laccase/TEMPO catalytic system in aqueous medium
Gotor-Fernandez, Vicente,Diaz-Rodriguez, Alba,Lavandera, Ivan,Kanbak-Aksu, Seda,Sheldon, Roger A.,Gotor, Vicente
, p. 3405 - 3408 (2013/02/22)
An efficient catalytic system to oxidize quantitatively aliphatic diols using Trametes versicolor laccase and TEMPO has been developed in aqueous medium. Oxidations have occurred in a non-stereoselective fashion but with complete regio- and/or monoselectivity, obtaining lactones with excellent purity after simple extraction. This catalytic system has been demonstrated to be scalable, compatible with the presence of a variety of functionalities, and also allowed the successful enzyme recycling using a laccase-cross-linked enzyme aggregates (CLEA) preparation.
