56661-83-7Relevant academic research and scientific papers
Isothiocoumarin-3-carboxylic acid derivatives: Synthesis, anticancer and antitrypanosomal activity evaluation
Kaminskyy, Danylo,Kryshchyshyn, Anna,Nektegayev, Ihor,Vasylenko, Olexandr,Grellier, Philippe,Lesyk, Roman
, p. 57 - 66 (2014/03/21)
A series of new isothiocoumarin-3-carboxylic acids derivatives had been obtained based on the 5-arylidenerhodanines hydrolysis. Anticancer activity screening allowed identification of 7,8-dimethoxy-1-oxo-1H-isothiochromene-3- carboxylic acid (4-phenylthia
The synthesis and SAR of rhodanines as novel class C β-lactamase inhibitors
Grant, Eugene B.,Guiadeen, Deodialsingh,Baum, Ellen Z.,Foleno, Barbara D.,Jin, Haiyong,Montenegro, Deborah A.,Nelson, Erin A.,Bush, Karen,Hlasta, Dennis J.
, p. 2179 - 2182 (2007/10/03)
β-Lactam antibiotics such as the cephalosporins and penicillins have diminished clinical effectiveness due to the hydrolytic activity of diverse β-lactamases, especially those in molecular classes A and C. A structure-activity relationship (SAR) study of
1-Oxo-1H-2-benzothiopyran-3-carboxylic acid derivatives
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, (2008/06/13)
The method comprises administering to an animal a novel pharmaceutical composition containing a substituted-1-oxo-1H-2-benzothiopyran-3-carboxylic acid to inhibit antigen-antibody reaction in said animal. Representative of the compounds that can be used i
