56671-82-0Relevant academic research and scientific papers
Industrial production method of 3-trifluoromethyl-2-cyclohexene-1-one
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Paragraph 0027-0029; 0033-0036, (2021/04/21)
The invention relates to an industrial production method of 3-trifluoromethyl-2-cyclohexene-1-one, which is prepared from 1, 3-cyclohexanedione through iodination and trifluoromethylation, has obviously higher yield than the prior art, does not need special reaction conditions such as high temperature, high pressure and the like, does not involve the use of heavy metal pollution reagents, and has the advantages of simple reaction and post-treatment and low cost. The product is easy to purify and suitable for industrial production.
Diastereo- and Enantioselective Cross-Couplings of Secondary Alkylcopper Reagents with 3-Halogeno-Unsaturated Carbonyl Derivatives
Kremsmair, Alexander,Skotnitzki, Juri,Knochel, Paul
supporting information, p. 11971 - 11973 (2020/09/07)
Chiral secondary alkylcopper reagents were prepared from the corresponding alkyl iodides with retention of configuration by an I/Li-exchange using tBuLi (?100 °C, 1 min) followed by a transmetalation with CuBr?P(OEt)3 (?100 °C, 20 s). These ste
3,4-DISUBSTITUTED 3-CYCLOBUTENE-1,2-DIONES AND USE THEREOF
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Paragraph 0544; 0545, (2019/02/24)
Described herein are compounds, or pharmaceutically acceptable salts thereof, of the following formula: The compounds are useful for treating inflammatory and autoimmune diseases.
Palladium-Catalyzed Ullmann Cross-Coupling of β-Iodoenones and β-Iodoacrylates with o-Halonitroarenes or o-Iodobenzonitriles and Reductive Cyclization of the Resulting Products to Give Diverse Heterocyclic Systems
Khan, Faiyaz,Dlugosch, Michael,Liu, Xin,Khan, Marium,Banwell, Martin G.,Ward, Jas S.,Carr, Paul D.
supporting information, p. 2770 - 2773 (2018/05/22)
The palladium-catalyzed Ullmann cross-coupling of β-iodoenones and β-iodoacrylates such as 5 (X = I) with o-halonitroarenes and o-iodobenzonitriles including 2 affords products such as compound 7. These can be engaged in a range of reductive cyclization r
Synthesis of β-chloro, β-bromo, and β-iodo α,β-unsaturated ketones
Piers, Edward,Grierson, John R.,Lau, Cheuk Kun,Nagakura, Isao
, p. 210 - 223 (2007/10/02)
A new, efficient method for the preparation of β-chloro, β-bromo, and β-iodo α,β-unsaturated ketones is described.The method involves the reaction of β-diketones or α-hydroxymethylenecycloalkanones with triphenylphosphine dihalides in the presence of trie
