56673-34-8

Basic information

• Product Name: 3-Bromo-6-mercaptopyridine
• Synonyms: 3-Bromo-6-mercaptopyridine;5-Bromopyridine-2-thiol;5-Bromo-2-mercaptopyridine;5-broMo-2(1H)-Pyridinethione;2(1H)-Pyridinethione, 5-broMo-
• CAS NO: 56673-34-8
• Molecular Formula: C₅H₄BrNS
• Molecular Weight: 190.06
• Product Categories: Heterocycle-Pyridine series
• Mol File: 56673-34-8.mol
• Article Data: 12

Chemical Properties

• Melting Point: 202-208°C
• Boiling Point: 246.5 °C at 760 mmHg
• Flash Point: 102.9 °C
• Appearance: /
• Density: 1.705 g/cm³
• Vapor Pressure: 0.0424mmHg at 25°C
• Refractive Index: 1.641
• Storage Temp.: Inert atmosphere,Room Temperature
• PKA: 8.09±0.40(Predicted)
• CAS DataBase Reference: 3-Bromo-6-mercaptopyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Bromo-6-mercaptopyridine(56673-34-8)
• EPA Substance Registry System: 3-Bromo-6-mercaptopyridine(56673-34-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-36/37/39
• WGK Germany: 3
• Hazardous Substances Data: 56673-34-8(Hazardous Substances Data)

Usage

General Description

3-Bromo-6-mercaptopyridine is an organosulfur compound that consists of a pyridine ring with a thiol group and a bromine atom attached to it. It is a yellowish solid that is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. 3-Bromo-6-mercaptopyridine has potential applications in the field of medicinal chemistry and drug design due to its ability to interact with biological targets such as enzymes and receptors. Additionally, 3-Bromo-6-mercaptopyridine can also be utilized as a precursor in the preparation of various organic molecules with desirable properties. However, it is important to handle this chemical with caution, as it may pose health hazards when not properly managed.

InChI:InChI=1/C5H4BrNS/c6-4-1-2-5(8)7-3-4/h1-3H,(H,7,8)

Upstream product

• 13466-38-1 5-bromopyridin-2(1H)-one 
• 766-11-0 5-bromo-2-fluoropyridine 
• 13466-38-1 5-bromopyridin-2-ol 
• 53939-30-3 5-bromo-2-chloropyridine 

Downstream Products

• 872273-36-4 5-bromo-2-(2-(5-bromopyridin-2-yl)disulfanyl)pyridine 
• 27012-25-5 5-bromo-2-phenylpyridine 
• 19520-27-5 5-bromo-2-(phenylthio)pyridine 
• 1645264-12-5 N-benzyl-5-bromo-2-pyridinesulfenamide 
• 494772-73-5 5-bromo-2-(cyclopropylmethylthio)pyridine 
• 874959-68-9 5-bromopyridine-2-sulfonyl chloride 
• 15827-72-2 2,5-diphenylpyridine 

Relevant articles and documents

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with a defect in glyoxylate metabolism, for example a disease or disorder associated with the enzyme glycolate oxidase (GO) or alterations in oxalate metabolism. Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

GLYCOLATE OXIDASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme glycolate oxidase (GO). Such diseases or disorders include, for example, disorders of glyoxylate metabolism, including primary hyperoxaluria, that are associated with production of excessive amounts of oxalate.

Silver-induced self-immolative Cl-F exchange fluorination of arylsulfur chlorotetrafluorides: Synthesis of arylsulfur pentafluorides

A novel strategy for the synthesis of arylsulfur pentafluorides by silver carbonate-induced Cl-F exchange fluorination of arylsulfur chlorotetrafluorides is reported. This fluorination does not require any exogenous fluoride sources. Rather, the reaction proceeds via the self-immolation of the substrate Ar-SF4Cl.