56684-87-8

Usage

Uses

Used in Pharmaceutical Applications:
Batatasin III is used as an inhibitor in the pharmaceutical industry for its potential therapeutic effects. It has been identified as a new dormancy-inducing substance of yam bulbils, which suggests its role in regulating biological processes related to growth and development.
Used in Anticancer Research:
Although not explicitly mentioned in the provided materials, Batatasin III's structure and properties may suggest potential applications in cancer research. Its ability to act as an inhibitor could be harnessed to target specific proteins or enzymes involved in cancer cell growth and proliferation, making it a candidate for further investigation in oncology.
Used in Agricultural Applications:
As a dormancy-inducing substance, Batatasin III could be utilized in the agricultural industry to control the growth and dormancy cycles of yam and potentially other crops. This application could help optimize crop production and storage, leading to improved yields and reduced waste.

InChI:InChI=1/C16H18O3/c1-18-15-5-3-4-12(9-15)6-7-13-8-14(17)11-16(10-13)19-2/h3-5,8-11,17H,6-7H2,1-2H3

Upstream product

• 1700-37-4 3-Benzyloxybenzaldehyde 
• 58026-13-4 1-(benzyloxy)-3-(bromomethyl)-5-methoxybenzene 
• 50637-28-0 (3-(benzyloxy)-5-methoxyphenyl)methanol 

Downstream Products

• 101330-71-6 1,3-dimethoxy-5-(3-methoxyphenethyl)benzene 

Relevant academic research and scientific papers

Naturally occurring Batatasins and their derivatives as α-glucosidase inhibitors

Batatasins are endogenous plant hormones found in yams and other related plant species. These plants are widely consumed as botanical dietary supplements in many parts of the world. This study investigated the inhibitory effects and mechanisms of Batatasin I, III, IV, V against α-glucosidase regarding their antidiabetic activities. The results revealed that Batatasin I, III, IV inhibited α-glucosidase in a reversible and noncompetitive manner, with IC50 values of 2.55, 1.89 and 2.52 mM respectively, while Batatasin V completely abolished its inhibitory activity even at the highest concentrations tested. Furthermore, a class of Batatasin-derived compounds with different substitution patterns was synthesized and subjected to the assay to clarify the structure-activity relationships, which suggested that the hydroxyl at the C-2′ position may play a significant role in improving the inhibitory activities. Their probable binding modes and the specificity of the binding sites were studied using molecule docking simulation. It was concluded that Batatasins, especially Batatasin III and IV, are promising α-glucosidase inhibitors, which therefore could be used as functional food to alleviate postprandial hyperglycemia and as potential candidates for the development of antidiabetic agents.

Two bibenzyl glucosides from Pleione bulbocodioides

From the tubers of Pleione bulbocodioides, two novel bibenzyl glucosides, together with their known aglycones, batatasin III and 3'-O- methylbatatasin III, were isolated. The new glycosides were 3'-hydroxy-5- methoxybibenzyl-3-O-β-D-glucopyranoside and 3',5-dimethoxybibenzyl-3-O-β- D-glucopyranoside on the basis of their spectroscopic data.