56686-55-6

Usage

Uses

Used in Environmental and Biological Studies:
1,1,1,3-Tetrachloroundecane is used as a reference chemical for evaluating the genotoxicity and toxicity in primary hepatocyte cultures of humans and lab animals. Its application aids in understanding the potential harmful effects of environmental pollutants on liver cells and contributes to the development of safety measures and regulations.
Used as a Persistent Environmental Pollutant:
1,1,1,3-Tetrachloroundecane is recognized as a persistent environmental pollutant. Its presence in the environment is utilized to study the long-term effects of pollutants on ecosystems and human health. This knowledge is crucial for developing strategies to mitigate the impact of such pollutants and protect the environment and public health.

Upstream product

• 56-23-5 tetrachloromethane 
• 872-05-9 1-Decene 
• 2547-61-7 Trichloromethanesulfonyl chloride 

Relevant academic research and scientific papers

Assessment of catalysis by arene-ruthenium complexes containing phosphane or NHC groups bearing pendant conjugated diene systems

Two p-cymene-ruthenium complexes 1 and 2 were isolated in high yields by treating the [RuCl2(p-cymene)]2 dimer with new hybrid phosphane- or NHC-linked diene ligands. Both complexes were fully characterized by NMR spectroscopy, and the molecular structure of the ruthenium-p-cymene complex 1, containing the phosphane-diene ligand system, was determined by X-ray diffraction analysis. The catalytic activities of both compounds were probed in atom-transfer radical addition (ATRA) and polymerization (ATRP), in the cyclopropanation of olefins, in the ring-opening metathesis polymerization (ROMP) of norbornene, and in the synthesis of enol esters from hex-1-yne and 4-acetoxybenzoic acid.

Hydration of alkenes and cycloalkenes in the presence of chromium and copper complexes

Chromium and copper complexes catalyzed hydration of acyclic and cyclic olefins in the presence of carbon tetrachloride at 110-160 C (4-12 h) with formation of the corresponding alcohols.

Atom transfer radical addition (ATRA) of carbon tetrachloride and chlorinated esters to various olefins catalyzed by Cp′Ru(PPh 3)(PR3)Cl complexes

CpRu(PPh3)(PR3)Cl complexes, where PR 3 = PMe3, PPh3, or PTA (PTA = 1,3,5-triaza-7-phosphaadamantane), were used to catalyze the atom transfer radical addition of chlorinated esters (CClsu

Chlorination of various substrates in subcritical carbon tetrachloride

Various aliphatic hydrocarbons and the side chains of aromatic hydrocarbons were chlorinated in subcritical carbon tetrachloride. Chlorination of aromatic compounds including 1,4-disubstituted benzenes was investigated. Ketones and sulfones were stable under the employed conditions. Sulfoxides were converted into sulfides in a low to modest yields. The coupling adducts between olefins and carbon tetrachloride were obtained from the reactions of olefins.

An efficient, selective, and reducing agent-free copper catalyst for the atom-transfer radical addition of halo compounds to activated olefins

Efficient and selective ATRA reactions of CCl4, CBr4, TsCl (Ts = tosyl), or Cl3CCO2Et with activated olefins (styrene, methyl methacrylate, n-butyl methacrylate, ferf-butyl methacrylate) using the TptBuCu(NCMe) complex as a catalyst have been achieved In the absence of any reductant and with low catalyst loadings.

Addition of CCl4 to olefins catalyzed by chromium and ruthenium complexes: The influence of water as a nucleophilic additive

The feasibility of the addition of CCl4 to linear and cyclic olefins and dienes in the presence of chromium and ruthenium complexes was established. The influence of water as a nucleophilic additive and the influence of the olefin nature, the c

Highly efficient ambient-temperature copper-catalyzed atom-transfer radical addition (ATRA) in the presence of free-radical initiator (V-70) as a reducing agent

Highly efficient, ambient-temperature, copper-catalyzed Atom Transfer Radical Addition (ATRA) of polyhalogenated compounds to alkenes in the presence of free radical initiator 2,2' -azobis (4-methoxy-2,4-dimethyl valeronitrile)(V-70)as a reducing agent was reported. The discrepancies between the alkene conversion and percent yield were mostly due to competing free-radical polymerization. ATRA of polyhalogenated compounds to monomers that are highly active in free-radical polymerization was not successful at 60 ° C when AIBN was used as radical initiator. The V-70 was proved to be very effective reducing agent, enabling selective formation of the monoadduct with α -olefins and highly active monomers such as methyl acrylate, methyl methacrylate, and vinyl acetate. The methodology for catalyst regeneration in copper-mediated ATRA in the presence of V-70 as a reducing agent also worked very well in the addition of CCl4 and CBr4 to highly active vinyl acetate.

Chlorination of aliphatic hydrocarbons, aromatic compounds, and olefins in subcritical carbon tetrachloride

The reactions of various substrates including aliphatic hydrocarbons, aromatic compounds, and olefins were investigated in subcritical carbon tetrachloride. Ketones and sulfones were stable under the employed conditions. The coupling adducts between olefins and carbon tetrachloride were obtained from the reactions of olefins.

Microwave-enhanced ruthenium-catalysed atom transfer radical additions

The first monomode microwave-assisted atom transfer radical additions (ATRA) of carbon tetrachloride to various olefins were successfully performed, affording the adducts with almost quantitative yields in less than 10 min at 160 °C.

Atom-transfer radical addition (ATRA) and cyclization (ATRC) reactions catalyzed by a mixture of [RuCl2Cp*(PPh3)] and magnesium

A new catalytic procedure for atom-transfer radical addition (ATRA) and cyclization (ATRC) reactions is described. The combination of the ruthenium(III) complex [RuCl2-Cp*(PPh3)] (Cp*: pentamethylcyclopentadienyl) with magnesium allows these reactions to be performed under mild conditions with high efficiency. In most cases, the catalyst concentrations required are significantly lower than those used in previously reported procedures. It is suggested that magnesium acts as a reducing agent that generates and regenerates the catalytically active ruthenium(II) species. The precatalyst [RuCl2Cp*(PPh 3)] has been analyzed by X-ray crystallography.