56691-71-5Relevant academic research and scientific papers
Cyclohexenonic long-chain fatty alcohols as neuronal growth stimulators
Luu, Bang,Gonzalez De Aguilar, Jose-Luis,Girlanda-Junges, Celine
, p. 1439 - 1460 (2007/10/03)
Neurotrophic factors play an important role in the development and maintenance of neurons, thus providing a suitable therapeutic approach for the treatment of neurodegenerative diseases. However, their clinical use has revealed problematic because of a number of technical and biological disadvantages. Among the different strategies proposed to overcome such difficulties, the search for non-peptide substances with neurotrophic potential is giving promising results. Here we will expose major findings in this field, drawing special attention to cyclohexenonic long-chain fatty alcohols, a novel family of compounds that promote neuronal survival and neurite outgrowth.
3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one and its effect on neuropeptide secretion
Girlanda-Junges, Celine,Lutz-Bucher, Bernadette,Gonzalez de Aguilar, Jose-Luis,Loeffler, Jean-Philippe,Luu, Bang
, p. 2537 - 2539 (2007/10/03)
The aim of the present study was to describe the synthesis of a trimethyl cyclohexenonic long chain fatty alcohol (t-CFA), and analyze its biological activity. Specifically, 3-(15-hydroxypentadecyl)-2,4,4-trimethyl-2-cyclohexen-1-one, the t-CFA containing
Superacidic low temperature cyclization of terpenylphenyisulfones
Kulcitki, Veaceslav,Ungur, Nicon,Vlad, Pavel F.
, p. 11925 - 11934 (2007/10/03)
The superacidic cyclization of aliphatic and partially cyclized C10- C20 terpenylphenylsulfones proceeds structure-selectively and stereospecifically, affording α- or mixtures of α- and γ-isomers of completely cyclized terpenylphenylsulfones. The configuration of the phenylsuffonylmethylene group in the cyclized products is predetermined by the configuration of the allylic double bond in the starting compounds.
