566934-67-6

Basic information

• Product Name: ethyl 2-O-acetyl-3-O-benzyl-4-(2,4-O-benzylidene-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-1-thio-α-D-mannopyranoside
• Synonyms: ethyl 2-O-acetyl-3-O-benzyl-4-(2,4-O-benzylidene-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-1-thio-α-D-mannopyranoside
• CAS NO: 566934-67-6
• Molecular Weight: 529.654
• Mol File: 566934-67-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-O-acetyl-3-O-benzyl-4-(2,4-O-benzylidene-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-1-thio-α-D-mannopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-O-acetyl-3-O-benzyl-4-(2,4-O-benzylidene-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-1-thio-α-D-mannopyranoside(566934-67-6)
• EPA Substance Registry System: ethyl 2-O-acetyl-3-O-benzyl-4-(2,4-O-benzylidene-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-1-thio-α-D-mannopyranoside(566934-67-6)

Safety Data

• Hazardous Substances Data: 566934-67-6(Hazardous Substances Data)

Upstream product

• 115234-11-2 ethyl 2-O-acetyl-4-azido-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside 
• 566934-88-1 (3R)-1,3-O-benzylidine-1,3,4-butanetriol 
• 566934-90-5 2,4-O-benzylidene-3-deoxy-L-glycero-tetronic acid 
• 566934-66-5 ethyl 4-amino-2-O-acetyl-3-O-benzyl-4,6-dideoxy-1-thio-α-D-mannopyranoside 

Downstream Products

• 566934-73-4 5-methoxycarbonylpentyl 3-O-benzyl-4-(2,4-O-benzylidene-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-α-D-mannopyranosyl-(1->2)-3-O-benzyl-4-(2,4-O-benzylidene-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-α-D-mannopyranoside 
• 566934-72-3 5-methoxycarbonylpentyl 2-O-acetyl-3-O-benzyl-4-(2,4-O-benzylidene-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-α-D-mannopyranosyl-(1->2)-3-O-benzyl-4-(2,4-O-benzylidene-3-deoxy-L-glycero-tetronamido)-4,6-dideoxy-α-D-mannopyranoside 

Relevant articles and documents

Neoglycoconjugates from synthetic tetra- and hexasaccharides that mimic the terminus of the O-PS of Vibrio cholerae O:1, serotype Inaba

A glycosyl acceptor and a glycosyl donor having the N-3-deoxy-L-glycero-tetronic acid side chain already attached have been prepared and used for the synthesis of the di- through to the hexasaccharide that mimic the upstream terminus of the O-specific polysaccharide of Vibrio cholerae O:1, serotype Inaba. The target tetra- and the hexasaccharide, which were obtained in the form of 5-methoxycarbonylpentyl glycosides, were linked to BSA using squaric acid diester chemistry. The conjugation reactions were monitored by surface enhanced laser desorption ionization-time of flight mass spectrometry (SELDI-TOF MS). This allowed the progression of the conjugation of the synthetic oligosaccharides in a controlled way and termination of the reaction when the desired molar hapten/BSA ratio had been reached, yielding neoglycoconjugates with predetermined carbohydrate/carrier ratios. The ability to monitor the conjugation by the SELDI-TOF MS technique made it possible to prepare, from one hapten in a one-pot reaction, several neoglycoconjugates having different, predetermined carbohydrate/carrier ratios.