566949-69-7Relevant academic research and scientific papers
Improved syntheses of morinol C and D by employing mizoroki-heck reaction and their cytotoxic and antimicrobial activities
Ogura, Koji,Sugahara, Takuya,Maruyama, Masafumi,Akiyama, Koichi,Yamauchi, Satoshi
experimental part, p. 1641 - 1644 (2011/05/30)
Improved syntheses of optically pure (-)- and (+)- morinol C, and (-)- and (+)-morinol D were achieved by employing the Mizoroki-Heck reaction to construct the cinnamyl moiety. The protective group of the alkene substrate affected the yield of this key re
Syntheses of the stereoisomers of neolignans morinol C and D
Yamauchi, Satoshi,Uno, Hidemitsu
, p. 1323 - 1329 (2007/10/03)
Morinol C and morinol D are neolignans isolated from the Chinese medicinal herb Morina chinensis as racemates. (1R,2R)-Morinol C and (1S,2R)-morinol D were synthesized from (+)-(3R,4R)-4-(3,4-dimethoxyphenyl)-3-pivaloyloxymethyl-4-butanolide 4. On the other hand, (1S,2S)-morinol C and (1R,2S)-morinol D were synthesized from anti-aldol product 8.
