56703-31-2Relevant academic research and scientific papers
BIAROMATIC COMPOUNDS THAT MODULATE PPAR TYPE RECEPTORS, PROCESS FOR PREPARING THEM AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS
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Page/Page column 44; 1/2, (2010/11/08)
The invention relates to novel biaromatic compounds that correspond to the general formula (I) and also to the method for preparing them, and to their use in pharmaceutical compositions for use in human or veterinary medicine, especially in dermatology, a
11,12-Secoprostaglandins. 6. Interphenylene Analogues of Acylhydroxyalkanoic Acids and Related Compounds as Renal Vasodilators
Bicking, John B.,Robb, Charles M.,Cragoe, Edward J.,Blaine, Edward H.,Watson, L. Sherman,Dunlay, Mary C.
, p. 335 - 341 (2007/10/02)
The synthesis is described of a series of interphenylene analogues of the modified 11,12-secoprostaglandins and their sulfonamide isosteres on which we have reported previously.The new compounds are formally derived from members of earlier series by replacement of segments of the methylene chains by phenylene units.Several of these compounds displayed renal vasodilatory activity on iv stat administration to anesthetized dogs. 4-(4-Acetyl-8-hydroxytridecyl)benzoic acid tested additionally in conscious dogs orally caused a significant increase in renal blood flow at 5 mg/kg.
Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins
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, (2008/06/13)
Interphenylene 8-aza-9-dioxothia-11,12-secoprostaglandins are prepared by the two-stage alkylation of the anion of a lower alkyl sulfonamide, R1 SO2 NH2, using first a compound of the formula: STR1 and second, a compound o
Novel cyclopentane derivatives
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, (2008/06/13)
The present invention relates to novel not naturally occurring 10,11-dihydro-derivatives of prostaglandins of the A-series as well as a process for their preparation. The compounds of the invention have an antiprostaglandin effect and may be used as medicaments for the inhibition or suppression pharmacological properties of the prostaglandins.
