56718-05-9Relevant academic research and scientific papers
Hydroformylation of cinnamic acid derivatives catalyzed by rhodium complexes
Botteghi, C.,Paganelli, S.
, p. C18 - C21 (1993)
The hydroformylation of methyl cinnamate catalyzed by various rhodium complexes affords the aldehyde 1a with good chemo- and regio-selectivity, while in the case of methyl p-chlorocinnamate the predominant reaction is the substrate hydrogenation. Higher yields of the desired aldehydes 1a and 1b are obtained by hydroformylation of the cinnamaldehyde and p-chlorocinnamaldehyde diethylacetal, respectively, under the same reaction conditions. These aldehyde products are valuable drug precursors.
