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Ethyl (2Z)-2-[(4,5-dimethoxy-2-nitrophenyl)methylidene]-5-(3,4-dimethoxyphenyl)-7-methyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate is a complex organic compound with a molecular formula of C26H24N2O9S. It is characterized by a thiazolo[3,2-a]pyrimidine core structure, which is fused with a pyrimidine ring. The molecule features a 2,3-dihydro-5H configuration, indicating the presence of a double bond between the 2nd and 3rd carbon atoms, and a 3-oxo group, suggesting a carbonyl group at the 3rd position. The compound also includes a 2Z configuration, indicating the presence of a (Z)-alkene isomer. It has a 7-methyl group attached to the core structure and two methoxy-substituted phenyl rings, one at the 4,5-positions and the other at the 3,4-positions. The molecule is further functionalized with a nitro group at the 2-position of the 4,5-dimethoxyphenyl ring and a carboxylate group at the 6-position of the thiazolo[3,2-a]pyrimidine ring, which is esterified with an ethyl group. ethyl (2Z)-2-[(4,5-dimethoxy-2-nitrophenyl)methylidene]-5-(3,4-dimethoxyphenyl)-7-methyl-3-oxo-2,3-dihydro-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate is likely to be a pharmaceutical or chemical intermediate due to its complex structure and functional groups, which can be involved in various chemical reactions and biological activities.

5673-99-4

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5673-99-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 5673-99-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,7 and 3 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 5673-99:
(6*5)+(5*6)+(4*7)+(3*3)+(2*9)+(1*9)=124
124 % 10 = 4
So 5673-99-4 is a valid CAS Registry Number.

5673-99-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name ethyl 2-[(4,5-dimethoxy-2-nitrophenyl)methylidene]-5-(3,4-dimethoxyphenyl)-7-methyl-3-oxo-5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate

1.2 Other means of identification

Product number -
Other names 2,3-dimethyl-pent-4-en-1-ol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:5673-99-4 SDS

5673-99-4Downstream Products

5673-99-4Relevant academic research and scientific papers

COMPOUNDS THAT INHIBIT MCL-1 PROTEIN

-

Page/Page column 2330; 2331, (2017/09/15)

Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.

Condensation de reactifs organomagnesiens sur les bromhydrines du type R-CH(Br)-CH2OH. Influence des sels cuivreux.

Bourgain-Commercon, Monique,Normant, Jean F.

, p. 289 - 294 (2007/10/02)

Various allylic, vinylic and arylic Grignard reagents are able to condense with 2-bromo-1-alkanols in THF.The catalytic use of copper salts diminishes side reactions but is not required.

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