5674-04-4Relevant articles and documents
Copper-catalyzed asymmetric conjugate addition with Grignard reagents and SimplePhos ligands
Palais, Laetitia,Alexakis, Alexandre
experimental part, p. 2866 - 2870 (2010/04/05)
Herein we report the copper-catalyzed asymmetric conjugate addition of Grignard reagents to cyclic and acyclic enones, with SimplePhos as chiral ligands. A variety of Grignard reagents can be added to a range of cyclic and acyclic enones, with moderate to good enantioselectivities (ee's up to 86%).
ALKYL METAL ASYMMETRIC REDUCTION. 11. THE REACTION OF α,β-UNSATURATED KETONES WITH β-BRANCHED TRIALKYLALUMINIUM COMPOUNDS.
Giacomelli, Giampaolo,Caporuso, Anna Maria,Lardicci, Luciano
, p. 3663 - 3666 (2007/10/02)
The reduction of a series of α,β-unsaturated ketones has been studied under various experimental conditions, by using β-branched trialkylalanes.Asymmetric induction phenomena are observed when optically active trialkylalanes are used.