56741-33-4Relevant academic research and scientific papers
Mutasynthesis of fluorinated pactamycin analogues and their antimalarial activity
Almabruk, Khaled H.,Lu, Wanli,Li, Yuexin,Abugreen, Mostafa,Kelly, Jane X.,Mahmud, Taifo
supporting information, p. 1678 - 1681 (2013/07/05)
A mutasynthetic strategy has been used to generate fluorinated TM-025 and TM-026, two biosynthetically engineered pactamycin analogues produced by Streptomyces pactum ATCC 27456. The fluorinated compounds maintain excellent activity and selectivity toward chloroquine-sensitive and multidrug-resistant strains of malarial parasites as the parent compounds. The results also provide insights into the biosynthesis of 3-aminobenzoic acid in S. pactum.
PYRROLO[2,3-B] PYRIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS
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Page/Page column 229, (2010/11/25)
Compounds of formula III which are active on protein kinases are described, as well as methods of using such compounds to treat diseases and conditions associated with aberrant activity of protein kinases.
Synthesis of 7-benzoxazol-2-yl and 7-Benzothiazol-2-yl-6-fluoro- quinolones
Richardson, Thomas O.,Shanbhag, Vinayak P.,Adair, Kimberly,Smith, Shantel
, p. 1301 - 1304 (2007/10/03)
The fluoroquinolones, 7-benzoxazol-2-yl-1-ethyl-6-fluoro-1,4-dihydro-4- oxoquinoline-3-carboxylic acid and 7-benzothiazol-2-yl-1-ethyl-6-fluoro-1,4- dihydro-4-oxoquinoline-3-carboxylic acid, were synthesized. The compounds were obtained, by use of the Gou
Sulfonanilide derivatives and medicine
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, (2008/06/13)
An object of the present invention is to offer an agent for curing urinary incontinence with high selectivity for the urethra. One of the compounds of the present invention is a sulfonanilide derivative having the following formula (I). STR1 The compounds
Mass Spectrometric Fragmentation Reactions. XXXI-The Fragmentation Behaviour of o-Halobenzoic Acids Substituted in the 5-Position: A Novel Ortho Effect
Breuer, M.,Budzikiewicz, H.
, p. 229 - 234 (2007/10/02)
A fragmentation sequence typical for o-halobenzoic acids carrying a heteroatom substituent in the 5-position is described.
