56741-77-6 Usage
Uses
Used in Synthetic Chemistry:
3,3’-di-tert-butyl oxaziridine is used as a reagent for amination, heteroatom transfer, and C-H functionalization in synthetic chemistry. Its application allows for the direct electrophilic primary and secondary amination of arylmetals in the presence of Cu(I) salts, eliminating the need for precious metal catalysts, ligands, protecting groups, or directing groups. This makes the process more efficient and cost-effective.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3,3’-di-tert-butyl oxaziridine is used as an intermediate for the synthesis of various drugs and drug candidates. Its unique reactivity and stability make it a valuable component in the development of new medications.
Used in Material Science:
3,3’-di-tert-butyl oxaziridine is also utilized in material science for the synthesis of novel materials with specific properties. Its incorporation into polymers and other materials can lead to enhanced performance characteristics, such as improved stability or reactivity.
Check Digit Verification of cas no
The CAS Registry Mumber 56741-77-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,7,4 and 1 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 56741-77:
(7*5)+(6*6)+(5*7)+(4*4)+(3*1)+(2*7)+(1*7)=146
146 % 10 = 6
So 56741-77-6 is a valid CAS Registry Number.
56741-77-6Relevant academic research and scientific papers
AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS
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Paragraph 0098; 0132; 0133, (2018/03/25)
In one aspect, the present disclosure provides methods of preparing a primary or secondary amine and hydroxylated aromatic compounds. In some embodiments, the aromatic compound may be unsubstituted, substituted, or contain one or more heteroatoms within the rings of the aromatic compound. The methods described herein may be carried out without the need for transition metal catalysts or harsh reaction conditions.
Non-deprotonative primary and secondary amination of (hetero)arylmetals
Zhou, Zhe,Ma, Zhiwei,Behnke, Nicole Erin,Gao, Hongyin,Kürti, László
supporting information, p. 115 - 118 (2017/05/16)
Herein we disclose a novel method for the facile transfer of primary (-NH2) and secondary amino groups (-NHR) to heteroaryl-as well as arylcuprates at low temperature without the need for precious metal catalysts, ligands, excess reagents, protecting and/or Erecting groups. This one-pot transformation allows unprecedented functional group tolerance and it is wellsuited for the amination of electron-rich, electron-deficient as well as structurally complex (hetero)arylmetals. In some of the cases, only catalytic amounts of a copper (l) salt is required.
