56746-18-0 Usage
Uses
Used in Agricultural Applications:
2,3-dichloro-N-(2',6'-diethylphenyl)maleimide is used as a pesticide for controlling a broad spectrum of insect and fungal pests on crops. Its application helps protect agricultural yields by reducing the damage caused by these pests, ensuring a more stable and productive food supply.
Used in Industrial Applications:
2,3-dichloro-N-(2',6'-diethylphenyl)maleimide is also utilized in the manufacturing of various industrial products, such as rubber, adhesives, and plastics. Its inclusion in these materials can enhance their properties, such as durability and resistance to degradation, making them more effective for their intended uses.
However, it is crucial to handle 2,3-dichloro-N-(2',6'-diethylphenyl)maleimide with care due to its toxicity to humans and the environment. Proper safety measures and regulations must be followed to minimize the potential risks associated with its use.
Check Digit Verification of cas no
The CAS Registry Mumber 56746-18-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,7,4 and 6 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 56746-18:
(7*5)+(6*6)+(5*7)+(4*4)+(3*6)+(2*1)+(1*8)=150
150 % 10 = 0
So 56746-18-0 is a valid CAS Registry Number.
56746-18-0Relevant articles and documents
Anti-leishmanial and cytotoxic activities of a series of maleimides: Synthesis, biological evaluation and structure-activity relationship
Fan, Yongxian,Lu, Yuele,Chen, Xiaolong,Tekwani, Babu,Li, Xing-Cong,Shen, Yinchu
, (2018/11/24)
In the present study, 45 maleimides have been synthesized and evaluated for anti-leishmanial activities against L. donovani in vitro and cytotoxicity toward THP1 cells. All compounds exhibited obvious anti-leishmanial activities. Among the tested compounds, there were 10 maleimides with superior anti-leishmanial activities to standard drug amphotericin B, and 32 maleimides with superior anti-leishmanial activities to standard drug pentamidine, especially compounds 16 (IC50 50 50 > 10 μg/mL). The anti-leishmanial activities of 16 and 42 were 10 times better than that of amphotericin B. The structure and activity relationship (SAR) studies revealed that 3,4-non-substituted maleimides displayed the strongest anti-leishmanial activities compared to those for 3-methyl-maleimides and 3,4-dichloro-maleimides. 3,4-dichloro-maleimides were the least cytotoxic compared to 3-methyl-maleimides and 3,4-non-substituted maleimides. The results show that several of the reported compounds are promising leads for potential anti-leishmanial drug development.
