56750-80-2

Basic information

• Product Name: (2,4-dimethylphenyl)(oxo)acetaldehyde
• Synonyms: benzeneacetaldehyde, 2,4-dimethyl-alpha-oxo-
• CAS NO: 56750-80-2
• Molecular Formula: C₁₀H₁₀O₂
• Molecular Weight: 162.1852
• Mol File: 56750-80-2.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 265.2°C at 760 mmHg
• Flash Point: 102.1°C
• Density: 1.075g/cm³
• Vapor Pressure: 0.00928mmHg at 25°C
• Refractive Index: 1.523
• CAS DataBase Reference: (2,4-dimethylphenyl)(oxo)acetaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: (2,4-dimethylphenyl)(oxo)acetaldehyde(56750-80-2)
• EPA Substance Registry System: (2,4-dimethylphenyl)(oxo)acetaldehyde(56750-80-2)

Safety Data

• Hazardous Substances Data: 56750-80-2(Hazardous Substances Data)

Usage

General Description

(2,4-dimethylphenyl)(oxo)acetaldehyde is a chemical compound with the molecular formula C10H10O2. It is an aromatic aldehyde, meaning it contains a benzene ring and a carbonyl group. The compound is commonly used as a fragrance additive in perfumes, soaps, and other personal care products. It also has applications in the production of pharmaceuticals and other fine chemicals. The chemical is a colorless liquid with a strong, sweet, floral odor, making it a popular choice for adding scent to various products. It is important to handle (2,4-dimethylphenyl)(oxo)acetaldehyde with care and use proper safety precautions due to its potential irritant properties and flammability.

Upstream product

• 89-74-7 2,4-dimethylacetophenone. 
• 108-38-3 m-xylene 
• 109300-46-1 2,2-dichloro-1-(2,4-dimethyl-phenyl)-ethanone 

Downstream Products

• 60814-26-8 2-(2,4-dimethyl-phenyl)-quinoxaline 
• 1638141-17-9 C₂₂H₁₈N₂O₃ 
• 1638141-39-5 C₂₂H₂₀N₂O₂ 

Relevant articles and documents

Ynonylation of Acyl Radicals by Electroinduced Homolysis of 4-Acyl-1,4-dihydropyridines

Herein we report the conversion of 4-Acyl-1,4-dihydropyridines (DHPs) into ynones under electrochemical conditions. The reaction proceeds via the homolysis of acyl-DHP under electron activation. The resulting acyl radicals react with hypervalent iodine(III) reagents to form the target ynones or ynamides in acceptable yields. This mild reaction condition allows wider functionality tolerance that includes halides, carboxylates, or alkenes. The synthetic utility of this methodology is further demonstrated by the late-stage modification of complex molecules.

Organocatalytic Enantioselective Acyloin Rearrangement of α-Hydroxy Acetals to α-Alkoxy Ketones

We report an unprecedented organocatalytic enantioselective acyloin rearrangement of α,α-disubstituted α-hydroxy acetals. In the presence of a catalytic amount of chiral binol-derived N-triflyl phosphoramide, α-hydroxy acetals rearranged to α-alkoxy ketones in good to high yields with high enantioselectivities. Formation of an ion pair between the in situ generated oxocarbenium ion and the chiral phosphoramide anion was proposed to be responsible for the highly efficient transfer of chirality. Conditions for removal of cyclohexyl and cyclopentyl groups from the corresponding α-alkoxy ketones were uncovered underpinning their potential general utility as hydroxy protecting groups. Conversion of the rearranged products to the enantioenriched α-hydroxy ketone, 1,2-diol, β-amino alcohol and 1,4-dioxane was also documented.

Unexplored reactivity of 2-oxoaldehydes towards Pictet-Spengler conditions: Concise approach to β-carboline based marine natural products

Novel reactions under Pictet-Spengler conditions between tryptophan methyl ester/tryptamine and 2-oxoaldehydes have been developed and successfully utilized for the total synthesis of Merinacarboline (A and B), Eudistomin Y1, Pityriacitrin B, Pityriacitrin, Fascaplysin and analogues.