56773-34-3

Basic information

• Product Name: 3-(TRIFLUOROMETHYLTHIO)PHENACYL BROMIDE
• Synonyms: 3-(TRIFLUOROMETHYLTHIO)PHENACYL BROMIDE;2-BROMO-3'-(TRIFLUOROMETHYLTHIO)ACETOPHENONE
• CAS NO: 56773-34-3
• Molecular Formula: C9H6BrF3OS
• Molecular Weight: 299.11
• Mol File: 56773-34-3.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-(TRIFLUOROMETHYLTHIO)PHENACYL BROMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(TRIFLUOROMETHYLTHIO)PHENACYL BROMIDE(56773-34-3)
• EPA Substance Registry System: 3-(TRIFLUOROMETHYLTHIO)PHENACYL BROMIDE(56773-34-3)

Safety Data

• Hazard Codes: C
• Hazardous Substances Data: 56773-34-3(Hazardous Substances Data)

Upstream product

• 56773-33-2 1-(3-((trifluoromethyl)thio)phenyl)ethan-1-one 

Downstream Products

• 956831-46-2 2-(2-amino-6-bromophenoxy)-1-(3-trifluoromethylsulfanylphenyl)ethanone 

Relevant articles and documents

Synthesis and discovery of 2,3-dihydro-3,8-diphenylbenzo[1,4]oxazines as a novel class of potent cholesteryl ester transfer protein inhibitors

2,3-Dihydro-3,8-diphenylbenzo[1,4]oxazines were identified as a new class of potent cholesteryl ester transfer protein inhibitors. The most potent compound 6a (IC50 = 26 nM) possessed a favorable pharmacokinetic profile with good oral bioavailability in rat (F = 53%) and long human liver microsome stability (t1/2 = 62 min). It increased HDL-C in human CETP transgenic mice and high-fat fed hamsters. The structure and activity relationship of this series will be described in this Letter.