56776-01-3 Usage
Uses
Hydrochloride salt of Tulobuterol a sympathomimetic drug used as a transdermal patch, increases normal diaphragm muscle strength. A β-adrenergic receptor agonist, related structurally to Terbutaline (T109750).
General Description
Standard for Supelco MIP SPE cartridges. For more information request Supelco Literature T407075, T706019, T706030, T706020
Check Digit Verification of cas no
The CAS Registry Mumber 56776-01-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,7,7 and 6 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 56776-01:
(7*5)+(6*6)+(5*7)+(4*7)+(3*6)+(2*0)+(1*1)=153
153 % 10 = 3
So 56776-01-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H18ClNO.ClH/c1-12(2,3)14-8-11(15)9-6-4-5-7-10(9)13;/h4-7,11,14-15H,8H2,1-3H3;1H/t11-;/m0./s1
56776-01-3Relevant articles and documents
Synthesis of the β2-Agonist Tulobuterol and Its Metabolite 4-Hydroxytulobuterol
Burdeinyi, M. L.,Glushkova, M. A.,Popkov, S. V.
, p. 390 - 394 (2020/04/27)
Abstract: Alternative methods have been developed for the synthesis of theβ2-agonist tulobuterol and its metabolite4-hydroxytulobuterol with a similar activity. The proposed procedures utilizeavailable reagents, and the key stage in the synthesis is the formation ofintermediate oxirane according to the Corey–Chaykovsky reaction, followed byopening of the oxirane ring by the action of excess tert-butylamine. In the synthesis of 4-hydroxytulobuterol, thehydroxy group was protected by benzylation, and the protecting group was removedin the final stage by hydrogenation over carbon-supported palladium.
