56776-32-0 Usage
Uses
Used in Pharmaceutical Research:
6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride is used as a γ-aminobutyric acid (GABA)-receptor agonist for studying its effects on insulin expression in α cell lines (αTC1). This application is crucial for understanding the role of GABA receptors in insulin regulation and their potential use in diabetes treatment.
Used in Psychotropic Drug Development:
As a psychotropic agent, 6-chloro-N-ethyl-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-amine monohydrochloride exhibits anxiolytic and anticonvulsant activity. Its ability to modulate GABA receptors makes it a promising candidate for the development of drugs targeting anxiety disorders and epilepsy, offering potential therapeutic benefits for patients suffering from these conditions.
Biochem/physiol Actions
Etifoxine is an anxiolytic anticonvulsant, which promotes axonal regeneration. It binds to β2 and β3 subunits of the GABAA receptor complex, a different target site to benzodiazepines, and binds to the translocator protein (18 kDa) TSPO, formerly known as the peripheral or mitochondrial benzodiazepine receptor. TSPO carries cholesterol from the outer to the inner mitochondrial membrane, which is the rate-limiting step of steroidogenesis. Whereas, its anxiolytic effects involve GABAA receptors and TSPO, etifoxine′s neuroregenerative effects mainly involve TSPO.
Check Digit Verification of cas no
The CAS Registry Mumber 56776-32-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,6,7,7 and 6 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 56776-32:
(7*5)+(6*6)+(5*7)+(4*7)+(3*6)+(2*3)+(1*2)=160
160 % 10 = 0
So 56776-32-0 is a valid CAS Registry Number.
InChI:InChI=1/C17H17ClN2O.ClH/c1-3-19-16-20-15-10-9-13(18)11-14(15)17(2,21-16)12-7-5-4-6-8-12;/h4-11H,3H2,1-2H3,(H,19,20);1H
