5680-51-3

Basic information

• Product Name: CYCLOPROPYL-(3-NITRO-PHENYL)-METHANONE
• Synonyms: CYCLOPROPYL-(3-NITRO-PHENYL)-METHANONE;Methanone, cyclopropyl(3-nitrophenyl)-
• CAS NO: 5680-51-3
• Molecular Formula: C₁₀H₉NO₃
• Molecular Weight: 191.18
• Mol File: 5680-51-3.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 285.9 °C at 760 mmHg
• Flash Point: 128.7 °C
• Appearance: /
• Density: 1.345 g/cm³
• Vapor Pressure: 0.00273mmHg at 25°C
• Refractive Index: 1.621
• Storage Temp.: 2-8°C
• CAS DataBase Reference: CYCLOPROPYL-(3-NITRO-PHENYL)-METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: CYCLOPROPYL-(3-NITRO-PHENYL)-METHANONE(5680-51-3)
• EPA Substance Registry System: CYCLOPROPYL-(3-NITRO-PHENYL)-METHANONE(5680-51-3)

Safety Data

• Hazardous Substances Data: 5680-51-3(Hazardous Substances Data)

Usage

General Description

Cyclopropyl-(3-nitro-phenyl)-methanone is an organic compound that belongs to the group of organic compounds known as nitrobenzenes. Its structure consists of a cyclopropyl group attached to a methanone, which is further linked to a phenyl group with a nitro group attached. It is characterized by the presence of a nitro group (-NO2) on the benzene ring, making it a nitroaromatic compound. The properties of this compound, such as stability, reactivity, and potential applications, would heavily depend on these structural elements. However, as a specific use or significant details about the cyclopropyl-(3-nitro-phenyl)-methanone seem to be not well-documented in the scientific literature, its exact applications and properties cannot be precisely defined.

InChI:InChI=1/C10H9NO3/c12-10(7-4-5-7)8-2-1-3-9(6-8)11(13)14/h1-3,6-7H,4-5H2

Upstream product

• 3481-02-5 cyclopropyl phenyl ketone 
• 7697-37-2 nitric acid 
• 4023-34-1 cyclopropanecarboxylic acid chloride 
• 645-00-1 m-iodonitrobenzene 
• 71-43-2 benzene 

Downstream Products

• 121-92-6 3-nitrobenzoic acid 
• 162169-82-6 3-(α-cyclopropyl-meta-(4-cyanophenylsulfonylamino)benzyl)-6-(α-ethylphenethyl)-4-hydroxy-2H-pyran-2-one 
• 162174-74-5 3-(α-cyclopropyl-meta-aminobenzyl)-6-(α-cyclopropylmethyl-cyclopropylethyl)-4-hydroxy-2H-pyran-2-one 
• 174485-01-9 3-(α-cyclopropyl-meta-(tert-butyloxycarbonylamino)benzyl)-6-(α-cyclopropylmethyl-cyclopropylethyl)-4-hydroxy-2H-pyran-2-one 
• 162170-49-2 3-(α-cyclopropyl-meta-(benzyloxycarbonylamino)benzyl)-6-(α-ethyl-phenethyl)-4-hydroxy-2H-pyran-2-one 
• 162174-72-3 3-(α-cyclopropyl-meta-aminobenzyl)-6-(α-ethyl-phenethyl)-4-hydroxy-2H-pyran-2-one 

Relevant articles and documents

Synthesis of Polyfunctional Diorganomagnesium and Diorganozinc Reagents through In Situ Trapping Halogen–Lithium Exchange of Highly Functionalized (Hetero)aryl Halides in Continuous Flow

We report a halogen–lithium exchange performed in the presence of various metal salts (ZnCl2, MgCl2?LiCl) on a broad range of sensitive bromo- or iodo(hetero)arenes using BuLi or PhLi as the exchange reagent and a commercially available continuous-flow setup. The resulting diarylmagnesium or diarylzinc species were trapped with various electrophiles, resulting in the formation of polyfunctional (hetero)arenes in high yields. This method enables the functionalization of (hetero)arenes containing highly sensitive groups such as an isothiocyanate, nitro, azide, or ester. A straightforward scale-up was possible without further optimization.

PYRANONE COMPOUNDS USEFUL TO TREAT RETROVIRAL INFECTIONS

The present invention relates to compounds of formulae (I) and (II) which are pyran-2-ones, 5,6-dihydro-pyran-2-ones, 4-hydroxy-benzopyran-2-ones, 4-hydroxy-cycloalkyl[b]pyran-2-ones, and derivatives thereof, useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus, wherein R 10 and R 20 taken together are formulae (III) and (IV). STR1

4-HYDROXY-BENZOPYRAN-2-ONES AND 4-HYDROXY-CYCLOALKYL[B]PYRAN-2-ONES USEFUL TO TREAT RETROVIRAL INFECTIONS

The present invention relates to compounds of formula I which are 4-hydroxy-benzopyran-2-ones and 4-hydroxy-cycloalkyl[b]pyran-2-ones useful for inhibiting a retrovirus in a mammalian cell infected with said retrovirus. STR1 Wherein R 10 and R 20 taken together are: STR2