5681-57-2 Usage
Chemical Class
Urea derivatives
A group of organic compounds with a specific functional group, in this case, 1-butyl-3-hydroxyurea is a part of this class.
Molecular Weight
132.16 g/mol
The mass of one mole of 1-butyl-3-hydroxyurea, which is 132.16 grams.
Usage in Pharmaceutical Industry
Antineoplastic and Antiviral Agent
1-butyl-3-hydroxyurea has potential applications in the pharmaceutical industry as a drug that can inhibit the growth of cancer cells and viruses.
Laboratory Results
Inhibition of Cancer Cell and Virus Growth
In laboratory studies, 1-butyl-3-hydroxyurea has shown promising results in inhibiting the growth of cancer cells and viruses, indicating its potential as a therapeutic agent.
Potential Application
Sickle Cell Disease Treatment
Researchers have investigated the use of 1-butyl-3-hydroxyurea in treating sickle cell disease by inducing the production of fetal hemoglobin, which could alleviate the symptoms of the disease.
Research Status
Ongoing
Further research is necessary to fully understand the potential uses and safety profile of 1-butyl-3-hydroxyurea, as its effects and applications are not yet completely known.
Check Digit Verification of cas no
The CAS Registry Mumber 5681-57-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,6,8 and 1 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 5681-57:
(6*5)+(5*6)+(4*8)+(3*1)+(2*5)+(1*7)=112
112 % 10 = 2
So 5681-57-2 is a valid CAS Registry Number.
5681-57-2Relevant academic research and scientific papers
A convenient method for the synthesis of N-hydroxyureas
Parrish, Dennis A.,Zou, Zhou,Allen, C. Leigh,Day, Cynthia S.,King, S. Bruce
, p. 8841 - 8843 (2007/10/03)
Treatment of amines with 1-(4-nitrophenol)-N-(O-benzylhydroxy)carbamate yields the O-benzyl protected N-hydroxyureas. Hydrogenation of the O-benzyl protected N-hydroxyureas over 5% Pd/BaSO4 cleanly gives the N-hydroxyureas in good yield. In add
N-substituted hydroxyureas as urease inhibitors
Uesato, Shinichi,Hashimoto, Yuichiro,Nishino, Masaru,Nagaoka, Yasuo,Kuwajima, Hiroshi
, p. 1280 - 1282 (2007/10/03)
In order to seek a urease inhibitor more potent than hydroxyurea (1), its alkyl- or phenyl-substituted derivatives were synthesized and evaluated for their effect on the jack bean urease. Of 16 compounds tested, m-methyl-(10) and m-methoxy-phenyl substituted hydroxyurea (13) showed the most potent inhibitory activities against the enzyme.
Synthesis and evaluation of new sulfur-containing L-arginine-derived inhibitors of nitric oxide synthase
Ichimori, Kohji,Stuehr, Dennis J.,Atkinson, Robert N.,King, S. Bruce
, p. 1842 - 1848 (2007/10/03)
A series of compounds (7, 8, 10-17, 23) containing new functional groups derived by the combination of the substrate, intermediate, product, and known inhibitors of nitric oxide synthase (NOS) were prepared and evaluated against NOS. While none of the com
