56827-92-0

Basic information

• Product Name: Phosphoric acid, hexadecyl diphenyl ester
• Synonyms: Phosphoric acid, hexadecyl diphenyl ester
• CAS NO: 56827-92-0
• Molecular Formula: C₂₈H₄₃O₄P
• Molecular Weight: 474.62
• Mol File: 56827-92-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 527.6°C at 760 mmHg
• Flash Point: 285.9°C
• Appearance: /
• Density: 1.031g/cm³
• Vapor Pressure: 1.08E-10mmHg at 25°C
• Refractive Index: 1.508
• CAS DataBase Reference: Phosphoric acid, hexadecyl diphenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphoric acid, hexadecyl diphenyl ester(56827-92-0)
• EPA Substance Registry System: Phosphoric acid, hexadecyl diphenyl ester(56827-92-0)

Safety Data

• Hazardous Substances Data: 56827-92-0(Hazardous Substances Data)

Usage

Uses

Hexadecyl Diphenyl Phosphate has been used in the preparation of synthetic analogues of Irlbacholine, which is a novel antifungal plant metabolite isolated from Irlbachia Alata.

InChI:InChI=1/C28H43O4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-21-26-30-33(29,31-27-22-17-15-18-23-27)32-28-24-19-16-20-25-28/h15-20,22-25H,2-14,21,26H2,1H3

Upstream product

• 36653-82-4 1-Hexadecanol 
• 2524-64-3 chlorophosphoric acid diphenyl ester 
• 544-77-4 1-iodohexadecane 

Downstream Products

• 736906-37-9 Phosphoric acid 4-benzyloxy-cyclohexyl ester hexadecyl ester 
• 3539-43-3 hexadecyl dihydrogen phosphate 

Relevant articles and documents

Inhibition of human erythrocyte membrane phosphatidylinositol 4-kinase by phospholipid analogues

Analogues of phosphatidylinositol (PtdIns, 1) have been synthesized to investigate the structural requirements for inhibition of a PtdIns 4-kinase obtained from human erythrocyte membranes. While the presence of either D-1 or D-3 stereochemistry in the inositol moiety greatly influences the degree of inhibition produced by PtdIns analogues, the stereochemistry of the glycerol moiety is of little consequence. Neither structural feature however, makes a significant contribution to binding affinity. Competitive inhibitory activity was found to be retained (or even enhanced) in substantially simpler analogues consisting of 1 or 2 hydrocarbon chains attached to a charged phosphate head group, such as in the phosphatidic acids, 24 and 26. The observation that the phosphatidylinositol 4-phosphate (PtdIns 4P) and phosphatidic acid analogues (eg, 16 or 17, and 26 respectively) inhibit PtdIns 4-kinase may suggest that such species have a regulatory role in PtdIns turnover.