568565-33-3Relevant academic research and scientific papers
4-Aryl-3-(hydroxyalkyl)quinolin-2-ones: Novel maxi-K channel opening relaxants of corporal smooth muscle targeted for erectile dysfunction
Hewawasam, Piyasena,Fan, Wenhong,Ding, Min,Flint, Kim,Cook, Deborah,Goggins, Gregory D.,Myers, Robert A.,Gribkoff, Valentin K.,Boissard, Christopher G.,Dworetzky, Steven I.,Starrett Jr., John E.,Lodge, Nicholas J.
, p. 2819 - 2822 (2007/10/03)
Novel 4-aryl-3-(hydroxyalkyl)quinoline-2-one derivatives were prepared and evaluated as openers of the cloned maxi-K channel hSlo expressed in Xenopus laevis oocytes by utilizing electrophysiological methods. The effect of these maxi-K openers on corporal
