568565-48-0Relevant academic research and scientific papers
Asymmetric synthesis of (+)- and (-)-latifine
Couture, Axel,Deniau, Eric,Grandclaudon, Pierre,Lebrun, Stephane
, p. 1309 - 1316 (2003)
A concise and novel synthesis of isoquinoline alkaloids (S)-latifine and of its antipode is reported. The key step relies on the stereoselective reduction of an appropriately substituted diarylenamine equipped with a chiral auxiliary followed by Pictet-Sp
A new synthesis of (+)- and (-)-cherylline.
Lebrun, Stephane,Couture, Axel,Deniau, Eric,Grandclaudon, Pierre
, p. 1701 - 1706 (2007/10/03)
A new and concise synthesis of enantiopure antipodes of alkaloid cherylline has been devised. The synthetic strategy relies upon the reduction of a diversely and polyprotected diarylenamine bearing a chiral auxiliary. Separation of diastereopure intermediates, concomitant deprotections and intramolecular reductive amination complete the synthesis of the natural (S)-enantiomer and of the unnatural (R)-configured antipode.
